Target Name: XK
NCBI ID: G7504
Other Name(s): neurocanthocytosis | truncated X-linked Kx blood group | XKR1 | XK-related protein 1 | kell complex 37 kDa component | Kell blood group precursor (McLeod phenotype) | XK, Kell blood group complex subunit (McLeod syndrome) | truncated XK protein | X1k | Kx blood group antigen | XK_HUMAN | Membrane transport protein XK | NA__4663 | NAC | Endoplasmic reticulum membrane adapter protein XK | NA | X-linked Kx blood group antigen, Kell and VPS13A binding protein | Kx antigen | KX | Kell complex 37 kDa component

Understanding Neurocanthocytosis: Potential Drug Targets

XK is a protein that is expressed in the central nervous system (CNS) and is known as neurocanthocytosis. It is a condition that is characterized by the accumulation of dead red blood cells (red cells) in the brain and other parts of the body. This accumulation can cause a variety of symptoms, including symptoms of neurological and psychiatric disorders.

The neurocanthocytosis protein is a protein that is produced by the liver and is then transported to the CNS. It is involved in the development and maintenance of the blood-brain barrier, which is a barrier that separates the brain from the surrounding body. The blood-brain barrier helps to protect the brain from harmful substances and allows it to function properly.

One of the main challenges in the treatment of neurocanthocytosis is the difficulty in reaching the affected areas of the brain. Because the brain is surrounded by the blood-brain barrier, it is difficult to deliver drugs and other treatments to the affected areas. This makes it difficult to effectively treat the symptoms of neurocanthocytosis.

In recent years, researchers have been studying the neurocanthocytosis protein and have identified several potential drug targets. These drug targets include the neurocanthocytosis protein itself, as well as genes that are associated with the production of the protein.

One potential drug target for neurocanthocytosis is the neurocanthocytosis protein itself. Researchers have identified several small molecules that can interact with the neurocanthocytosis protein and cause it to change shape. These small molecules are thought to be able to inhibit the activity of the neurocanthocytosis protein and potentially treat neurocanthocytosis.

Another potential drug target for neurocanthocytosis is the gene that is associated with the production of the neurocanthocytosis protein. Researchers have identified several genetic mutations that are associated with the production of neurocanthocytosis protein. These mutations may be able to be used to identify potential drug targets for neurocanthocytosis.

In addition to drug targets, researchers have also been studying the neurocanthocytosis protein in order to better understand its role in the development and progression of neurocanthocytosis. This research is helping to identify new potential drug targets and is also providing insights into the underlying mechanisms that cause neurocanthocytosis.

Overall, the neurocanthocytosis protein is a promising drug target for the treatment of neurocanthocytosis. Further research is needed in order to fully understand its role and to identify effective treatments.

Protein Name: X-linked Kx Blood Group Antigen, Kell And VPS13A Binding Protein

Functions: Recruits the lipid transfer protein VPS13A from lipid droplets to the endoplasmic reticulum (ER) membrane

More Common Targets

XKR3 | XKR4 | XKR5 | XKR6 | XKR7 | XKR8 | XKR9 | XKRX | XKRY | XKRYP7 | XLOC_007697 | XLOC_008559 | XLOC_009911 | XNDC1N | XPA | XPC | XPC complex | XPNPEP1 | XPNPEP2 | XPNPEP3 | XPO1 | XPO4 | XPO5 | XPO6 | XPO7 | XPOT | XPR1 | XRCC1 | XRCC2 | XRCC3 | XRCC4 | XRCC5 | XRCC6 | XRCC6P5 | XRN1 | XRN2 | XRRA1 | XXYLT1 | XXYLT1-AS2 | XYLB | XYLT1 | XYLT2 | YAE1 | YAF2 | YAP1 | YARS1 | YARS2 | YBEY | YBX1 | YBX1P1 | YBX1P10 | YBX1P2 | YBX1P4 | YBX2 | YBX3 | YBX3P1 | YDJC | YEATS2 | YEATS4 | YES1 | YIF1A | YIF1B | YIPF1 | YIPF2 | YIPF3 | YIPF4 | YIPF5 | YIPF6 | YIPF7 | YJEFN3 | YJU2 | YJU2B | YKT6 | YLPM1 | YME1L1 | YOD1 | YPEL1 | YPEL2 | YPEL3 | YPEL3-DT | YPEL4 | YPEL5 | YRDC | YTHDC1 | YTHDC2 | YTHDF1 | YTHDF2 | YTHDF3 | YWHAB | YWHABP1 | YWHAE | YWHAEP1 | YWHAEP7 | YWHAG | YWHAH | YWHAH-AS1 | YWHAQ | YWHAQP6 | YWHAZ | YWHAZP2