ECHDHC3: Enoyl CoA Hydratase Domain Containing 3 (G79746)

Target Name: ECHDC3

NCBI ID: G79746

Other Name(s): Enoyl CoA hydratase domain containing 3 | FLJ20909 | Enoyl Coenzyme A hydratase domain containing 3 | enoyl Coenzyme A hydratase domain containing 3 | testis tissue sperm-binding protein Li 76m | ECHD3_HUMAN | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial precursor | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial | enoyl-CoA hydratase domain containing 3

ECHDHC3: Enoyl CoA Hydratase Domain Containing 3

Enoyl CoA hydratase domain containing 3 (ECHDHC3) is a protein that is expressed in various tissues and cells throughout the body. It plays a crucial role in the metabolism of fatty acids, including the conversion of fatty acids into energy in the form of ATP.

ECHDHC3 is a member of the Enoyl CoA hydratase family, which is a group of enzymes that are involved in the breakdown of fatty acids to produce energy in the form of ATP. This family of enzymes includes ECDHC1, ECDHC2, and ECDHC3, which are all characterized by the presence of a hydratase domain.

The hydratase domain is a key structural feature that is responsible for the formation of a hydrate bond between the fatty acid and the substrate. This bond is formed by a condensation of the substrate's carbonyl group and the water molecule, resulting in the formation of an ionic bond.

ECHDHC3 is a 18-kDa protein that is expressed in various tissues and cells throughout the body. It is highly conserved, with a calculated molecular weight of 21.4 kDa and a calculated pI of 7.1. ECDHC3 is found in various cellular organelles, including mitochondria, endoplasmic reticulum, and cytosol.

ECHDHC3 is involved in the metabolism of fatty acids, including the conversion of fatty acids into energy in the form of ATP. It is a key enzyme in the citric acid cycle, which is the central metabolic pathway that is responsible for the production of energy from fatty acids.

In addition to its role in the citric acid cycle, ECDHC3 is also involved in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of cell adhesion, cell migration, and the modulation of cellular signaling pathways, including the TGF-β pathway.

ECHDHC3 is also a potential drug target and biomarker. Its involvement in the production of ATP from fatty acids makes it an attractive target for drugs that are designed to enhance the production of ATP in cells. Additionally, its role in the regulation of cellular signaling pathways makes it a potential target for drugs that are designed to modulate these pathways.

In conclusion, ECDHC3 is a protein that is expressed in various tissues and cells throughout the body. It is a key enzyme in the citric acid cycle and is involved in the production of ATP from fatty acids. Its role in the regulation of cellular signaling pathways makes it an attractive target for drugs that are designed to enhance the production of ATP and modulate cellular signaling pathways. Further research is needed to fully understand the mechanisms of ECDHC3 and its potential as a drug target and biomarker.

Protein Name: Enoyl-CoA Hydratase Domain Containing 3

Functions: May play a role in fatty acid biosynthesis and insulin sensitivity

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