EEF1A1P11: A Potential Drug Target and Biomarker in Eukaryotes

Target Name: EEF1A1P11

NCBI ID: G440595

Other Name(s): eukaryotic translation elongation factor 1 alpha 1 pseudogene 11 | Eukaryotic translation elongation factor 1 alpha 1 pseudogene 11 | EEF1AL9

EEF1A1P11: A Potential Drug Target and Biomarker in Eukaryotes

The eukaryotic translation elongation factor 1 alpha 1 pseudogene 11 (EEF1A1P11) is a non-coding RNA molecule that plays a critical role in the regulation of protein translation in eukaryotic cells. It is a key component of the eukaryotic translation machinery, which is responsible for the production of functional proteins from mRNAs. Mutations in the EEF1A1P11 gene have been linked to various diseases, including cancer, neurodegenerative diseases, and developmental disorders. Therefore, targeting this gene has the potential to be a valuable drug or biomarker.

The EEF1A1P11 gene is located on chromosome 19q31 and has 21 coding exons. It is part of the large heat shock protein (LSP) family, which are involved in the regulation of protein stability and localization in the cytosol. EEF1A1P11 is a putative pseudogene, which means that it is a non-coding gene that has the potential to code for a protein.

Expression of EEF1A1P11 is regulated by various factors, including translation factors, nuclear factors, and post-transcriptional modifications. It is a highly expressed gene in most eukaryotic organisms, including humans. It is expressed in a variety of tissues and organs, including brain, heart, muscle, and tissues, indicating its importance in various cellular processes.

Mutations in the EEF1A1P11 gene have been linked to various diseases, including cancer, neurodegenerative diseases, and developmental disorders. For example, a missense mutation in the EEF1A1P11 gene has been linked to the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Similarly, a missense mutation in the EEF1A1P11 gene has also been linked to the development of cancer, including colon cancer.

Targeting EEF1A1P11 as a drug or biomarker has the potential to be a valuable therapeutic approach for treating various diseases. For example, if EEF1A1P11 is targeted as a drug, it could potentially be used to treat neurodegenerative diseases by preventing the misfolding of protein and reducing neurodegeneration. Similarly, if EEF1A1P11 is used as a biomarker, it could be used to diagnose and monitor various diseases, including cancer.

In conclusion, EEF1A1P11 is a non-coding RNA molecule that plays a critical role in the regulation of protein translation in eukaryotic cells. Its mutations have been linked to various diseases, including cancer and neurodegenerative diseases. Therefore, targeting this gene as a drug or biomarker has the potential to be a valuable therapeutic approach for treating various diseases. Further research is needed to determine the full role of EEF1A1P11 in cellular processes and its potential as a drug or biomarker.

Protein Name: Eukaryotic Translation Elongation Factor 1 Alpha 1 Pseudogene 11

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