Target Name: NPRL3
NCBI ID: G8131
Other Name(s): Nitrogen permease regulator 3-like protein | Nitrogen permease regulator-like 3 (S. cerevisiae), transcript variant 2 | conserved gene telomeric to alpha globin cluster | alpha-globin regulatory element-containing gene protein | Nitrogen permease regulator 3-like protein (isoform 2) | GATOR complex protein NPRL3 (isoform 1) | MARE | Conserved gene telomeric to alpha globin cluster | C16orf35 | Protein CGTHBA | -14 gene protein | NPR3 | NPRL3 variant 1 | NPR3 like, GATOR1 complex subunit, transcript variant 1 | RMD11 | NPR3 like, GATOR1 complex subunit | NPRL3 variant 2 | NPRL3_HUMAN | CGTHBA | FFEVF3 | Alpha-globin regulatory element-containing gene protein | HS-40 | GATOR complex protein NPRL3

NPRL3: A Potential Drug Target and Biomarker

Nitrogen (N) is a vital compound in all living organisms, and it plays a critical role in various cellular processes. The Nitrogen permease regulator 3-like protein (NPRL3) is a protein that is expressed in various cell types of the human body. It is a member of the superfamily of cytoskeletal protein, which is involved in the regulation of cell division, growth, and differentiation. In this article, we will discuss the research on NPRL3 and its potential as a drug target or biomarker.

Potential Drug Target

NPRL3 is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and kidney. It is involved in the regulation of cell growth, differentiation, and reproduction. Several studies have suggested that NPRL3 may have potential as a drug target due to its unique structure and its involvement in various cellular processes.

One of the potential drug targets for NPRL3 is its role in cell proliferation. NPRL3 has been shown to regulate the growth and proliferation of various cancer cell types. For instance, a study by Kim et al. (2014) found that NPRL3 was downregulated in various cancer cell types, and overexpression of the protein was associated with cancer cell proliferation.

Another potential drug target for NPRL3 is its role in cell migration. NPRL3 has been shown to regulate the migration of various cell types, including cancer cells. For instance, a study by Zhao et al. (2018) found that NPRL3 was involved in the regulation of cell migration and that its expression was downregulated in various cancer cell types.

Potential Biomarker

NPRL3 may also be potential as a biomarker for various diseases, including cancer. Its involvement in the regulation of cellular processes makes it a potential biomarker for various diseases. For instance, a study by Zhang et al. (2020) found that NPRL3 was downregulated in various cancer cell types, and overexpression of the protein was associated with cancer progression.

Another potential use of NPRL3 as a biomarker is its involvement in the regulation of inflammation. NPRL3 has been shown to regulate the production of pro-inflammatory cytokines, such as TNF-alpha and IL-18. For instance, a study by Wang et al. (2020) found that NPRL3 was involved in the regulation of TNF-alpha and IL-18 production in various cell types, including immune cells.

Conclusion

In conclusion, NPRL3 is a protein that is expressed in various tissues of the human body and is involved in the regulation of cellular processes. Its unique structure and involvement in various cellular processes make it a potential drug target and biomarker. Further research is needed to fully understand its role in the regulation of cellular processes and its potential as a drug target and biomarker.

Protein Name: NPR3 Like, GATOR1 Complex Subunit

Functions: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway

More Common Targets

NPS | NPSR1 | NPSR1-AS1 | NPTN | NPTN-IT1 | NPTX1 | NPTX2 | NPTXR | NPVF | NPW | NPY | NPY1R | NPY2R | NPY4R | NPY4R2 | NPY5R | NPY6R | NQO1 | NQO2 | NR0B1 | NR0B2 | NR1D1 | NR1D2 | NR1H2 | NR1H3 | NR1H4 | NR1I2 | NR1I3 | NR2C1 | NR2C2 | NR2C2AP | NR2E1 | NR2E3 | NR2F1 | NR2F1-AS1 | NR2F2 | NR2F2-AS1 | NR2F6 | NR3C1 | NR3C2 | NR4A1 | NR4A2 | NR4A3 | NR5A1 | NR5A2 | NR6A1 | NRAD1 | NRADDP | NRAP | NRARP | NRAS | NRAV | NRBF2 | NRBF2P4 | NRBP1 | NRBP2 | NRCAM | NRDC | NRDE2 | NREP | NRF1 | NRG1 | NRG2 | NRG3 | NRG4 | NRGN | NRIP1 | NRIP2 | NRIP3 | NRIP3-DT | NRIR | NRK | NRL | NRM | NRN1 | NRN1L | NRON | NRP1 | NRP2 | NRROS | NRSN1 | NRSN2 | NRSN2-AS1 | NRTN | NRXN1 | NRXN2 | NRXN2-AS1 | NRXN3 | NSA2 | NSA2P2 | NSD1 | NSD2 | NSD3 | NSDHL | NSF | NSFL1C | NSFP1 | NSG1 | NSG2 | NSL complex