NRG4: Cell Adhesion, Cellular Regulation, Cell Death and Cell Migration

Target Name: NRG4

NCBI ID: G145957

NRG4: Cell Adhesion, Cellular Regulation, Cell Death and Cell Migration

Neuregulin 4 (NRG4) is a protein that is expressed in various tissues throughout the body, including the nervous system, endothelial cells, and epithelial cells. Its function is not well understood, but it is known to be involved in several important cellular processes that are critical for normal development, wound healing, and tissue repair.

One of the key functions of NRG4 is its role in cell-cell adhesion. This is the process by which cells stick together to form tissues and organs, and it is a critical aspect of development and wound healing. NRG4 is involved in the formation of tight junctions, which are the weakest type of cell-cell adhesion, and it is also involved in the removal of tight junctions during cell division.

Another function of NRG4 is its role in the regulation of cell proliferation. It is well known that cell proliferation is critical for the development and maintenance of tissues and organs, and NRG4 is involved in this process by regulating the production of a protein called S600, which is involved in cell proliferation.

NRG4 is also involved in the regulation of cell death. This is an important aspect of tissue repair and regeneration, and NRG4 is involved in this process by regulating the production of a protein called p53, which is involved in cell death.

In addition to its role in cell-cell adhesion, regulation of cell proliferation, and cell death, NRG4 is also involved in the regulation of cell migration. This is the process by which cells move from one location to another in the body, and it is a critical aspect of development and wound healing. NRG4 is involved in this process by regulating the production of a protein called vimentin, which is involved in cell migration.

Overall, NRG4 is a protein that is involved in several important cellular processes that are critical for normal development, wound healing, and tissue repair. As a drug target or biomarker, NRG4 may be a valuable target for the development of new therapies for a variety of diseases.

Protein Name: Neuregulin 4

Functions: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity)

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