LCOR: A MBLK-Family Protein with Potential as A Drug Target Or Biomarker

Target Name: LCOR

NCBI ID: G84458

LCOR: A MBLK-Family Protein with Potential as A Drug Target Or Biomarker

LCOR (mblk1-related protein 2) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the MBLK (Mucin-Binding Protein-Like) family, which includes proteins that are known to interact with mucins, a type of protein that is found in all body tissues and is involved in various functions, including cell signaling and tissue repair.

One of the functions of LCOR is to regulate the activity of a protein called TGDF (TGF-β1), which is a transcription factor that is involved in a variety of cellular processes, including cell signaling, DNA repair, and inflammation. TGF-β1 is a potent regulator of gene expression, and it has been implicated in the development and progression of many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

LCOR has been shown to play a role in the regulation of TGF-β1 activity, and it is thought to be a potential drug target or biomarker for a variety of diseases. For example, studies have shown thatLCOR is involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In addition, LCOR has been shown to be involved in the regulation of cancer cell growth and has been implicated in the development of certain types of cancer.

LCOR is also thought to be a potential biomarker for some diseases, as it can be expressed in a variety of tissues and can be targeted using small molecules or antibodies. For example, studies have shown that LCOR is expressed in the brains of individuals with Alzheimer's disease, and it has been suggested as a potential diagnostic biomarker for this disease. In addition, LCOR has been shown to be involved in the regulation of pain perception and has been implicated in the development of chronic pain conditions.

While more research is needed to fully understand the role of LCOR in these processes, it is clear that LCOR is a protein that is of great interest to researchers and clinicians. As such, it is worth further investigation as a potential drug target or biomarker for a variety of diseases.

Protein Name: Ligand Dependent Nuclear Receptor Corepressor

Functions: May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR

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