ZSCAN10: A Potential Drug Target and Biomarker (G84891)
ZSCAN10: A Potential Drug Target and Biomarker
Zinc finger and SCAN domain-containing protein 10 (ZSCAN10) is a protein that has been identified as a potential drug target and biomarker. Its unique structure and function have made it an attractive target for researchers to study. In this article, we will explore the research on ZSCAN10 and its potential as a drug target and biomarker.
Structure and Function
ZSCAN10 is a protein that contains a zinc finger and a SCAN domain. The zinc finger is a common structural feature that is found in many proteins, and it plays a role in protein-protein interactions. The SCAN domain is a small protein domain that is known for its ability to form a binary complex with other proteins. This domain is found in many proteins, including ZSCAN10, and it is involved in protein-protein interactions and regulation of protein function.
One of the unique features of ZSCAN10 is its ability to form a binary complex with the protein FBN1. FBN1 is a protein that is known for its role in blood clotting, and it is a potential drug target for many diseases, including heart disease and cancer. By forming a binary complex with FBN1, ZSCAN10 has the potential to interact with FBN1 and regulate its function, potentially leading to the inhibition of blood clots and the prevention of many diseases.
Another interesting feature of ZSCAN10 is its ability to form a ternary complex with the protein FBN1 and the protein HSP70B3. These interactions have been shown to play a role in the regulation of inflammation and fibrosis, and they may have implications for the treatment of many diseases.
Potential Drug Target
The unique structure and function of ZSCAN10 make it an attractive target for drug research. By inhibiting the activity of ZSCAN10, researchers may be able to treat many diseases that are currently untreated. One of the potential strategies for targeting ZSCAN10 is the use of small molecules, such as inhibitors of protein-protein interactions or inhibitors of the SCAN domain.
In addition to small molecules, researchers may also consider using other approaches to target ZSCAN10. These may include the use of antibodies or other proteins that can specifically recognize and interact with ZSCAN10. By using these approaches, researchers may be able to block the activity of ZSCAN10 and treat many diseases.
Biomarker
ZSCAN10 may also be used as a biomarker for the diagnosis and monitoring of many diseases. For example, the inhibition of ZSCAN10 activity by small molecules or antibodies may be used to treat blood clots or other cardiovascular diseases. In addition, the regulation of ZSCAN10 activity by FBN1 and HSP70B3 may be used to monitor the effectiveness of anti-inflammatory or anti-fibrotic treatments.
Conclusion
ZSCAN10 is a protein that has been identified as a potential drug target and biomarker. Its unique structure and function make it an attractive target for research into the treatment of many diseases. By inhibiting the activity of ZSCAN10, researchers may be able to treat a wide range of conditions, including blood clots, cardiovascular diseases, and inflammatory and fibrotic diseases. In addition, ZSCAN10 may also be used as a biomarker for the diagnosis and monitoring of many diseases.
Protein Name: Zinc Finger And SCAN Domain Containing 10
Functions: Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4
More Common Targets
ZSCAN12 | ZSCAN12P1 | ZSCAN16 | ZSCAN16-AS1 | ZSCAN18 | ZSCAN2 | ZSCAN20 | ZSCAN21 | ZSCAN22 | ZSCAN23 | ZSCAN25 | ZSCAN26 | ZSCAN29 | ZSCAN30 | ZSCAN31 | ZSCAN32 | ZSCAN4 | ZSCAN5A | ZSCAN5B | ZSCAN5DP | ZSCAN9 | ZSWIM1 | ZSWIM2 | ZSWIM3 | ZSWIM4 | ZSWIM5 | ZSWIM5P2 | ZSWIM6 | ZSWIM7 | ZSWIM8 | ZSWIM9 | ZUP1 | ZW10 | ZWILCH | ZWINT | ZXDA | ZXDB | ZXDC | ZYG11A | ZYG11B | ZYX | ZZEF1 | ZZZ3