ATP23: A Potential Drug Target for Cancer (G91419)
ATP23: A Potential Drug Target for Cancer
ATP23, also known as MGC134817, is a protein that is expressed in various tissues throughout the body. It is a key regulator of the DNA damage response, a process that helps the body repair itself when it experiences damage to its DNA. ATP23 has also has been shown to play a role in the regulation of cell signaling pathways, and is therefore considered a potential drug target (or biomarker).
Molecular structure of ATP23
ATP23 consists of 394 amino acids and its molecular weight is 41 kDa. It is a highly conserved protein whose structural domains include a short 伪-helix, a 尾-curl, a 纬-helix and a liquid domain. The liquid phase domain of ATP23 is a 110-amino-acid 伪-helix, which is composed of two 伪-helices, one of which is an 伪-helix composed of 4 amino acids, and the other is an 伪-helix composed of 3 amino acids.
Function of ATP23
ATP23 is a key regulator of DNA damage repair (DNA repair). DNA damage repair is an important process for cells to maintain genome integrity when they suffer DNA damage. When DNA damage occurs, ATP23 can help cells repair it and ensure the integrity of the genome.
ATP23 is also involved in the regulation of cell signaling. ATP23 plays an important role in multiple signaling pathways within cells, including cell cycle signaling, cell proliferation and apoptosis (apoptosis) signaling, and cellular immune signaling. ATP23 participates in cell growth, division, apoptosis and other processes by regulating key molecules in these signaling pathways.
Pharmacological significance of ATP23
Because ATP23 plays an important role in cells, it is considered a potential drug target (or biomarker). Many studies have shown that ATP23 is expressed in a variety of cancers and is closely related to cancer progression and treatment response.
For example, studies have shown that the expression level of ATP23 is positively correlated with the progression and treatment response of breast cancer. In addition, ATP23 is also closely related to the progression and treatment response of cancers such as ovarian cancer, colon cancer, and skin cancer.
In addition, ATP23 is also used as a biomarker for the treatment of certain cancers. For example, studies have shown that reduced ATP23 levels can serve as a biomarker for the treatment of certain skin cancers.
Biological significance of ATP23
ATP23 is a protein expressed in various tissues and plays an important role in cells. ATP23 can be used as a drug target (or biomarker) for the treatment of various cancers. With the in-depth study of ATP23 in drug screening and clinical trials, ATP23 may also become an important research topic and provide new ideas for cancer treatment.
Protein Name: ATP23 Metallopeptidase And ATP Synthase Assembly Factor Homolog
More Common Targets
ATP2A1 | ATP2A1-AS1 | ATP2A2 | ATP2A3 | ATP2B1 | ATP2B1-AS1 | ATP2B2 | ATP2B3 | ATP2B4 | ATP2C1 | ATP2C2 | ATP4A | ATP4B | ATP5F1A | ATP5F1B | ATP5F1C | ATP5F1D | ATP5F1E | ATP5F1EP2 | ATP5IF1 | ATP5MC1 | ATP5MC1P3 | ATP5MC2 | ATP5MC3 | ATP5ME | ATP5MF | ATP5MG | ATP5MGL | ATP5MJ | ATP5MK | ATP5PB | ATP5PBP5 | ATP5PD | ATP5PDP3 | ATP5PF | ATP5PO | ATP6 | ATP6AP1 | ATP6AP1-DT | ATP6AP1L | ATP6AP2 | ATP6V0A1 | ATP6V0A2 | ATP6V0A4 | ATP6V0B | ATP6V0C | ATP6V0CP1 | ATP6V0CP3 | ATP6V0D1 | ATP6V0D1-DT | ATP6V0D2 | ATP6V0E1 | ATP6V0E1P1 | ATP6V0E2 | ATP6V0E2-AS1 | ATP6V1A | ATP6V1B1 | ATP6V1B2 | ATP6V1C1 | ATP6V1C2 | ATP6V1D | ATP6V1E1 | ATP6V1E2 | ATP6V1F | ATP6V1FNB | ATP6V1G1 | ATP6V1G1P1 | ATP6V1G2 | ATP6V1G2-DDX39B | ATP6V1G3 | ATP6V1H | ATP7A | ATP7B | ATP8 | ATP8A1 | ATP8A2 | ATP8B1 | ATP8B1-AS1 | ATP8B2 | ATP8B3 | ATP8B4 | ATP8B5P | ATP9A | ATP9B | ATPAF1 | ATPAF2 | ATPase | ATPSCKMT | ATR | ATRAID | Atrial natriuretic peptide (ANP) receptor | ATRIP | ATRN | ATRNL1 | ATRX | ATXN1 | ATXN10 | ATXN1L | ATXN2 | ATXN2L