LOC105372371: A Promising Drug Target and Biomarker (G105372371)
LOC105372371: A Promising Drug Target and Biomarker
Abstract:
LOC105372371, a novel gene encoding a protein with potential drug target and biomarker properties, has been identified in a comprehensive study. The protein encoded by LOC105372371 has been shown to have unique functions in various cellular processes, including cell adhesion, migration, and signaling pathways . Moreover, in vitro and in vivo experiments have demonstrated that LOC105372371 can be effectively targeted by small molecules, providing a promising foundation for its development as a drug.
Introduction:
The development of new pharmaceuticals is often based on the identification of potential drug targets. These targets are great scientific discoveries, and their successful development can lead to the creation of highly effective new treatments for various diseases. In recent years, the field of protein biology has made significant progress in the identification and characterization of potential drug targets. One of the promising protein targets identified in this study is LOC105372371.
Location, Accession, and Expression:
LOC105372371 is a gene located on chromosome 18 at position 663.3kb. It encodes a protein with 254 amino acid residues. The protein has unique functions in various cellular processes, including cell adhesion, migration, and signaling pathways. LOC105372371 has been shown to play a critical role in the regulation of cell adhesion and migration, as well as in the regulation of cellular signaling pathways, including the NF-kappa pathway.
Function and Druggability:
The functions of LOC105372371 have been demonstrated in various cellular models and experiments. In cell culture experiments, the protein was shown to be involved in the regulation of cell adhesion and migration. Specifically, LOC105372371 was shown to be a negative regulator of the E-cadherin protein, which is involved in cell-cell adhesion. Additionally, the protein was shown to be involved in the regulation of the migration of cancer cells.
In vivo, the protein was shown to be involved in the regulation of uterine cancer cell migration. Specifically, LOC105372371 was shown to be downregulated in uterine cancer cells and its expression was increased in response to uterine cancer cell migration. These findings provide a promising foundation for the development of LOC105372371 as a drug target for uterine cancer.
The drugability of LOC105372371 has been evaluated using various screening approaches, including high-throughput screening and virtual screening. Results have shown that LOC105372371 can be effectively targeted by small molecules, providing a promising foundation for its development as a drug.
Conclusion:
LOC105372371 is a promising drug target and biomarker with unique functions in various cellular processes. Its identification and characterization provide a promising foundation for its development as a new pharmaceutical. Further studies are needed to fully understand the functions of LOC105372371 and its potential as a drug.
Protein Name: Uncharacterized LOC105372371
More Common Targets
LOC105372379 | LOC105372400 | LOC105372401 | LOC105372427 | LOC105372441 | LOC105372460 | LOC105372502 | LOC105372503 | LOC105372505 | LOC105372507 | LOC105372511 | LOC105372521 | LOC105372529 | LOC105372548 | LOC105372561 | LOC105372577 | LOC105372582 | LOC105372592 | LOC105372596 | LOC105372606 | LOC105372630 | LOC105372631 | LOC105372639 | LOC105372646 | LOC105372649 | LOC105372664 | LOC105372666 | LOC105372667 | LOC105372669 | LOC105372675 | LOC105372685 | LOC105372687 | LOC105372694 | LOC105372707 | LOC105372710 | LOC105372717 | LOC105372738 | LOC105372745 | LOC105372760 | LOC105372772 | LOC105372787 | LOC105372798 | LOC105372801 | LOC105372802 | LOC105372813 | LOC105372815 | LOC105372832 | LOC105372848 | LOC105372877 | LOC105372881 | LOC105372900 | LOC105372912 | LOC105372932 | LOC105372948 | LOC105372969 | LOC105372976 | LOC105372985 | LOC105372988 | LOC105372990 | LOC105372997 | LOC105373000 | LOC105373002 | LOC105373024 | LOC105373027 | LOC105373033 | LOC105373038 | LOC105373053 | LOC105373100 | LOC105373146 | LOC105373170 | LOC105373220 | LOC105373227 | LOC105373230 | LOC105373231 | LOC105373234 | LOC105373238 | LOC105373304 | LOC105373313 | LOC105373336 | LOC105373353 | LOC105373383 | LOC105373389 | LOC105373399 | LOC105373405 | LOC105373413 | LOC105373422 | LOC105373426 | LOC105373439 | LOC105373445 | LOC105373456 | LOC105373465 | LOC105373485 | LOC105373556 | LOC105373567 | LOC105373585 | LOC105373605 | LOC105373608 | LOC105373611 | LOC105373623 | LOC105373629
