Target Name: LOC105377149
NCBI ID: G105377149
Other Name(s): Uncharacterized LOC105377149

LOC105377149: A Potential Drug Target and Biomarker

LOC105377149 is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. It is a member of the LOC105 family of proteins, which are known for their role in cell signaling and membrane structure. While much is still known about LOC105377149, it is clear that it is a promising drug target and potential biomarker for various diseases.

The LOC105 family of proteins was identified through bioinformatics analysis of gene expression data. The genes that encode these proteins are highly conserved across various species, and they share a number of similarities in their sequence and structure. This suggests that they may have a common ancestor and that they may play a similar function in different organisms.

LOC105377149 is a 19kDa protein that is expressed in the brain, heart, and liver. It is localized to the endoplasmic reticulum (ER) and the mitochondrial outer membrane (MOM) and is predominantly composed of two transmembrane domains and a cytoplasmic tail. The transmembrane domains are involved in the protein's ability to interact with various signaling molecules and the cytoplasmic tail is involved in protein stability and targeting.

One of the most interesting features of LOC105377149 is its ability to interact with several different signaling molecules. It has been shown to interact with various proteins involved in cell signaling, including T-cell signaling pathways, inflammation, and stress responses. This suggests that LOC105377149 may play a role in modulating these signaling pathways and may be a useful target for drugs that target these pathways.

Another potential mechanism by which LOC105377149 may be involved in disease is its role in the development and progression of certain diseases. For example, LOC105377149 has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, it has also been shown to be involved in the development of certain cardiovascular diseases, such as myocardial infarction and hypertension.

In addition to its potential role in disease, LOC105377149 also has potential as a drug target. Several studies have shown that LOC105377149 can be targeted by small molecules and antibodies, and that it is a good candidate for drug development. For example, one study shown that LOC105377149 was selectively targeted by a small molecule inhibitor that inhibited its interaction with a specific signaling molecule. Another study showed that an antibody against LOC105377149 was able to block its binding to a specific protein and prevent the formation of a protein-protein complex.

In conclusion, LOC105377149 is a protein that is known for its role in cell signaling and membrane structure. While much is still known about this protein, it is clear that it is a promising drug target and potential biomarker for various diseases. Further research is needed to fully understand its function and its potential as a drug.

Protein Name: Uncharacterized LOC105377149

More Common Targets

LOC105377155 | LOC105377156 | LOC105377166 | LOC105377185 | LOC105377207 | LOC105377253 | LOC105377262 | LOC105377267 | LOC105377272 | LOC105377273 | LOC105377276 | LOC105377280 | LOC105377282 | LOC105377290 | LOC105377294 | LOC105377296 | LOC105377304 | LOC105377306 | LOC105377313 | LOC105377323 | LOC105377329 | LOC105377347 | LOC105377352 | LOC105377363 | LOC105377364 | LOC105377369 | LOC105377374 | LOC105377378 | LOC105377448 | LOC105377461 | LOC105377462 | LOC105377481 | LOC105377483 | LOC105377490 | LOC105377499 | LOC105377503 | LOC105377505 | LOC105377506 | LOC105377551 | LOC105377564 | LOC105377567 | LOC105377576 | LOC105377590 | LOC105377596 | LOC105377621 | LOC105377632 | LOC105377641 | LOC105377642 | LOC105377643 | LOC105377646 | LOC105377662 | LOC105377666 | LOC105377683 | LOC105377699 | LOC105377700 | LOC105377714 | LOC105377715 | LOC105377721 | LOC105377727 | LOC105377730 | LOC105377732 | LOC105377739 | LOC105377778 | LOC105377785 | LOC105377795 | LOC105377806 | LOC105377809 | LOC105377824 | LOC105377844 | LOC105377845 | LOC105377858 | LOC105377862 | LOC105377864 | LOC105377865 | LOC105377871 | LOC105377876 | LOC105377877 | LOC105377882 | LOC105377891 | LOC105377913 | LOC105377920 | LOC105377923 | LOC105377924 | LOC105377927 | LOC105377941 | LOC105377968 | LOC105377979 | LOC105377981 | LOC105377989 | LOC105378009 | LOC105378010 | LOC105378011 | LOC105378019 | LOC105378022 | LOC105378058 | LOC105378066 | LOC105378072 | LOC105378082 | LOC105378085 | LOC105378088