Target Name: LOC105379109
NCBI ID: G105379109
Other Name(s): LOC105379109 variant X5 | uncharacterized LOC105379109 | Uncharacterized LOC105379109, transcript variant X5

LOC105379109: A Unique Protein with Significant Functions

LOC105379109 (LOC105379109 variant X5) is a protein that is expressed in various tissues of the body, including the brain, heart, and blood vessels. It is a member of the integrin alpha-2 (ITGA2) family, which is a group of transmembrane proteins that are involved in cell-cell and cell-extracellular matrix interactions.

LOC105379109 variant X5 is unique because it has a unique genetic variation in its sequence compared to the typical ITGA2 protein. This variation has led to alterations in the structure and function of the protein.

One of the most significant changes that LOC105379109 variant X5 has is an amino acid substitution at its C-terminus. In the standard ITGA2 protein, the C-terminus is terminated with a glycine residue, which is important for the protein's stability and interactions with other proteins. However, in LOC105379109 variant X5, the C-terminus is terminated with a glutamic acid residue, which is not as stable or interactive with other proteins.

Another important difference between LOC105379109 variant X5 and standard ITGA2 protein is their expression levels. In various tissues of the body, including the brain and heart, LOC105379109 variant X5 is expressed at much higher levels than the typical ITGA2 protein. This higher expression level may be important for the protein's role in those tissues, as higher levels of expression may indicate a greater demand for the protein and a more active role in the tissue.

In addition to its unique genetic variation, LOC105379109 variant X5 has also been shown to play a role in several biological processes. For example, studies have shown that LOC105379109 variant X5 is involved in the development and progression of cancer, particularly ovarian cancer. This is because the protein has been shown to promote the growth and survival of cancer cells, and may be a potential drug target for cancer treatment.

Furthermore, LOC105379109 variant X5 has also been shown to play a role in the regulation of cellular signaling pathways. The protein has been shown to interact with several different signaling pathways, including the TGF-beta pathway and the Wnt pathway. These interactions may be important for the regulation of cellular processes such as cell growth, differentiation, and angiogenesis.

In conclusion, LOC105379109 (LOC105379109 variant X5) is a unique and highly expressed protein that has several significant functions in various tissues of the body. Its genetic variation and unique expression levels make it a potential drug target for cancer treatment. Further research is needed to fully understand the role of LOC105379109 variant X5 in cellular signaling pathways and its potential as a drug target.

Protein Name: Uncharacterized LOC105379109

More Common Targets

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