TREH: A Protein with Potential as A Drug Target Or Biomarker (G11181)

Target Name: TREH

NCBI ID: G11181

TREH: A Protein with Potential as A Drug Target Or Biomarker

TREH (Trehalase, transcript variant 1) is a protein that is expressed in various tissues and cells of the body. It is a member of the Trex family of proteins, which are involved in various cellular processes such as cell signaling, DNA replication, and transport. One of the unique features of TREH is its ability to catalyze the hydrolysis of trexin, a type of peptidic compound, to its active site, resulting in the formation of a 尾-sheet.

TREH is also known for its role in the regulation of gene expression and has been shown to play a role in the development and progression of various diseases. For example, TREH has been shown to be involved in the development of cancer, by promoting the growth and survival of cancer cells. Additionally, TREH has also been shown to contribute to the development of neurodegenerative diseases, by promoting the formation of neurofibrillary tangles in the brain.

Due to its unique structure and function, TREH has potential as a drug target or biomarker. Researchers are currently working to develop drugs that target TREH in order to treat various diseases, including cancer and neurodegenerative diseases.

One approach to developing drugs that target TREH is to use small molecules, such as inhibitors or modulators, that can modulate the activity of TREH. These small molecules can be designed to interact with specific regions of TREH, such as its active site or its substrate binding site. By modulating TREH's activity, researchers hope to achieve a range of therapeutic effects, such as inhibiting the growth of cancer cells or reducing the formation of neurofibrillary tangles in the brain.

Another approach to developing drugs that target TREH is to use proteins that can interact with TREH and modulate its activity. These proteins can be used as a scaffold to recruit TREH to its substrate, or they can interact with TREH to alter its activity. By using these proteins, researchers hope to achieve a range of therapeutic effects, such as enhancing the anticancer effects of TREH.

In addition to its potential as a drug target, TREH also has the potential as a biomarker. Its unique structure and function make it an attractive candidate for use as a diagnostic or diagnostic biomarker for various diseases. For example, TREH has been shown to be involved in the development of cancer, by promoting the growth and survival of cancer cells. By detecting TREH levels in cancer cells, researchers hope to use TREH as a diagnostic biomarker for cancer. Additionally, TREH has also been shown to contribute to the development of neurodegenerative diseases, by promoting the formation of neurofibrillary tangles in the brain. By detecting TREH levels in neurodegenerative disease samples, researchers hope to use TREH as a diagnostic biomarker for these diseases.

In conclusion, TREH is a protein that is expressed in various tissues and cells of the body and has the potential as a drug target or biomarker. Its unique structure and function make it an attractive candidate for use as a therapeutic or diagnostic agent. As research continues to advance, it is likely that TREH will play an increasingly important role in the development and treatment of various diseases.

Protein Name: Trehalase

Functions: Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose

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