Target Name: CKMT1B
NCBI ID: G1159
Other Name(s): CKMT | Acidic-type mitochondrial creatine kinase | UMTCK | Creatine kinase, mitochondrial 1 (ubiquitous) | Creatine kinase, ubiquitous mitochondrial | creatine kinase, mitochondrial 1 (ubiquitous) | Mia-CK | ubiquitous mitochondrial creatine kinase | CKMT1 | CKMT1A | mia-CK | Creatine kinase, mitochondrial 1B, transcript variant 1 | creatine kinase, mitochondrial 1B | Creatine kinase, mitochondrial 1B | U-MtCK | KCRU_HUMAN | Creatine kinase U-type, mitochondrial | acidic-type mitochondrial creatine kinase | Ubiquitous mitochondrial creatine kinase | CKMT1B variant 1

CKMT1B: Regulation of Cell Growth, Differentiation and Survival

CKMT1B (Cytoskeleton-associated protein kinase TKT1B) is a protein that is expressed in various tissues of the body, including muscle, brain, and heart. It is a member of the TKT family of proteins, which are involved in the regulation of cell growth, differentiation, and survival. CKMT1B is primarily localized to the cytoskeleton, where it plays a role in the organization and stability of muscle cells.

CKMT1B is a protein that is expressed in a wide range of tissues throughout the body, including muscle, brain, and heart. It is a member of the TKT family of proteins, which are involved in the regulation of cell growth, differentiation, and survival. CKMT1B is primarily localized to the cytoskeleton, where it plays a role in the organization and stability of muscle cells.

One of the primary functions of CKMT1B is to regulate the cytoskeleton organization and stability. The cytoskeleton is the protein structure that surrounds the cell and helps to maintain cell shape and provide structural support. CKMT1B is involved in the organization and stability of the cytoskeleton by participating in the formation of microtubules, which are the basic units of the cytoskeleton.

CKMT1B is also involved in the regulation of cell growth and differentiation. muscle cells, for example, need to be properly organized and shaped in order to function properly. CKMT1B helps to regulate the cytoskeleton organization and stability, which is necessary for the proper formation and maintenance of muscle cells.

CKMT1B is also involved in the regulation of cell survival. cells that are no longer needed or damaged are often programmed to die, a process called apoptosis. CKMT1B plays a role in the regulation of apoptosis by helping to ensure that cells that are no longer needed are properly targeted for death.

In addition to its role in cell regulation, CKMT1B is also considered a potential drug target. Its involvement in the regulation of cell growth, differentiation, and survival makes it a promising target for the development of new pharmaceuticals for a variety of diseases.

CKMT1B is also of interest in the context of cancer, as it has been shown to be often expressed in various types of cancer. This suggests that targeting CKMT1B may be a promising strategy for the development of new cancer therapies.

Overall, CKMT1B is a protein that plays a critical role in the regulation of cell growth, differentiation, and survival. Its involvement in the formation of microtubules, the regulation of apoptosis, and its involvement in cancer make it a promising target for the development of new pharmaceuticals. Further research is needed to fully understand the role of CKMT1B in the regulation of cell biology and to develop new treatments based on its unique properties.

Protein Name: Creatine Kinase, Mitochondrial 1B

Functions: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa

More Common Targets

CKMT2 | CKMT2-AS1 | CKS1B | CKS1BP2 | CKS1BP5 | CKS1BP6 | CKS1BP7 | CKS2 | CLASP1 | CLASP2 | CLASRP | Class III phosphatidylinositol 3-kinase (PI3-kinase) sub-complex | Clathrin | CLBA1 | CLC | CLCA1 | CLCA2 | CLCA3P | CLCA4 | CLCC1 | CLCF1 | CLCN1 | CLCN2 | CLCN3 | CLCN4 | CLCN5 | CLCN6 | CLCN7 | CLCNKA | CLCNKB | CLDN1 | CLDN10 | CLDN10-AS1 | CLDN11 | CLDN12 | CLDN14 | CLDN14-AS1 | CLDN15 | CLDN16 | CLDN17 | CLDN18 | CLDN19 | CLDN2 | CLDN20 | CLDN22 | CLDN23 | CLDN24 | CLDN25 | CLDN3 | CLDN34 | CLDN4 | CLDN5 | CLDN6 | CLDN7 | CLDN8 | CLDN9 | CLDND1 | CLDND2 | Cleavage and polyadenylation specificity factor complex | Cleavage factor Im complex | Cleavage Stimulation Factor | CLEC10A | CLEC11A | CLEC12A | CLEC12A-AS1 | CLEC12B | CLEC14A | CLEC16A | CLEC17A | CLEC18A | CLEC18B | CLEC18C | CLEC19A | CLEC1A | CLEC1B | CLEC2A | CLEC2B | CLEC2D | CLEC2L | CLEC3A | CLEC3B | CLEC4A | CLEC4C | CLEC4D | CLEC4E | CLEC4F | CLEC4G | CLEC4GP1 | CLEC4M | CLEC4OP | CLEC5A | CLEC6A | CLEC7A | CLEC9A | CLECL1P | CLGN | CLHC1 | CLIC1 | CLIC1P1 | CLIC2