Target Name: CMTM3
NCBI ID: G123920
Other Name(s): CKLF like MARVEL transmembrane domain containing 3 | OTTHUMP00000174790 | CKLF3_HUMAN | Chemokine-like factor superfamily member 3 | FLJ31762 | MGC51956 | CMTM3 variant 1 | chemokine-like factor superfamily member 3 | BNAS2 | CKLFSF3 | CKLF like MARVEL transmembrane domain containing 3, transcript variant 1 | CKLF-like MARVEL transmembrane domain-containing protein 3

Unlocking the Potential of CMTM3: A drug target and biomarker for MARVEL Transmembrane Domain Containing 3

The Marvel Transmembrane Domain Containing 3 (CMTM3) is a protein that plays a critical role in various cellular processes. It is a transmembrane protein that contains a unique Marvel Transmembrane Domain, which is known for its unique structure and function. Recently, research has identified CMTM3 as a potential drug target and biomarker for various diseases. In this article, we will delve into the details of CMTM3, its functions, and its potential as a drug target and biomarker.

Potential Drug Target

CMTM3 is a protein that is involved in various signaling pathways. It plays a critical role in the regulation of cell adhesion, migration, and invasion. CMTM3 is also involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. These functions make CMTM3 an attractive drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

CMTM3 is known for its unique Marvel Transmembrane Domain, which is composed of a series of conserved amino acids that form a hydrophobic region. This region is known for its ability to interact with various signaling molecules, including tyrosines and histidines. This interaction between CMTM3 and signaling molecules has led to the identification of CMTM3 as a potential drug target.

Potential Biomarker

CMTM3 has also been identified as a potential biomarker for various diseases. Its involvement in various signaling pathways makes it an attractive target for biomarkers that can be used to diagnose and monitor disease progression. For example, CMTM3 has been shown to be involved in the regulation of cancer cell migration and invasion. This makes it an potential biomarker for cancer, including brain metastases.

CMTM3 has also been shown to be involved in the regulation of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Its involvement in these diseases makes it an potential biomarker for these conditions.

Conclusion

In conclusion, CMTM3 is a protein that has the potential to be a drug target and biomarker for various diseases. Its unique Marvel Transmembrane Domain and involvement in various signaling pathways make it an attractive target for drug development. Further research is needed to fully understand the functions of CMTM3 and its potential as a drug target and biomarker.

Protein Name: CKLF Like MARVEL Transmembrane Domain Containing 3

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