CNTLN as A Potential Drug Target and Biomarker for Diseases (G54875)

Target Name: CNTLN

NCBI ID: G54875

CNTLN as A Potential Drug Target and Biomarker for Diseases

Centrin-like protein (CNTLN) is a protein that is found in the centrosome, which is a structure that is present in the nucleus of a cell. The centrosome is responsible for the proper organization of chromosomes during the cell's division, and it is a key player in the regulation of cell growth and division.

Recent studies have identified CNTLN as a potential drug target and biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders. This is because CNTLN has been shown to play a role in the regulation of cell growth, and its levels have been linked to the development and progression of these diseases.

One of the key reasons for the potential of CNTLN as a drug target is its role in the regulation of cell growth. CNTLN has been shown to play a role in the regulation of cell cycle progression, and it has been shown to disrupt the normal regulation of cell growth in a variety of ways. For example, one study found that CNTLN levels were significantly increased in breast cancer cells, and these levels were associated with the development of a more aggressive form of the disease.

Another potential drug target for CNTLN is its role in the regulation of neural development and function. Neural development and function are critical for the development and maintenance of normal brain function, and CNTLN has been shown to play a role in these processes. For example, one study found that CNTLN levels were significantly decreased in the brains of mice that had been genetically modified to exhibit neurodegenerative symptoms, and these levels were associated with the worsening of these symptoms.

In addition to its potential as a drug target, CNTLN has also been identified as a potential biomarker for a variety of diseases. For example, one study found that CNTLN levels were significantly increased in the brains of individuals with Alzheimer's disease, and these levels were associated with the severity of the disease. This suggests that CNTLN may be a useful biomarker for the diagnosis and treatment of Alzheimer's disease.

Another potential application of CNTLN as a drug target is its role in the regulation of cell division. CNTLN has been shown to play a role in the regulation of cell division in a variety of ways, and its levels have been linked to the development and progression of cancer. For example, one study found that CNTLN levels were significantly increased in cancer cells, and these levels were associated with the development of a more aggressive form of the disease.

Overall, CNTLN is a protein that has been shown to play a critical role in the regulation of cell growth, neural development and function, and cell division. As a result, it is a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of CNTLN in these processes and to develop effective treatments.

Protein Name: Centlein

Functions: Required for centrosome cohesion and recruitment of CEP68 to centrosomes

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