Target Name: COL1A2
NCBI ID: G1278
Other Name(s): Collagen alpha 2(I) chain | N-terminal propeptide of collagen alpha-2(I) chain | alpha-2 type I collagen | collagen of skin, tendon and bone, alpha-2 chain | epididymis secretory sperm binding protein | alpha 2(I)-collagen | EDSARTH2 | Collagen alpha-2(I) chain | collagen I, alpha-2 polypeptide | CO1A2_HUMAN | CO1A2(NP)_(HUMAN) | Alpha-2 type I collagen | type I procollagen | OI4 | collagen, type I, alpha 2 | alpha 2(I) procollagen | Collagen type I alpha 2 chain | EDSCV | alpha 2 type I procollagen | collagen type I alpha 2 chain

Unlocking the Potential of COL1A2: A novel Drug Target and Biomarker for Fibrosis and Chronic Pain

Introduction

Fibrosis and chronic pain are significant public health issues that affect millions of people worldwide. The uncontrolled growth of cells in the body, known as fibrosis, can lead to the loss of tissue, while chronic pain can significantly impact a person's quality of life. Although there are several treatments available for these conditions, the search for new, more effective approaches continues to be a major focus in the medical field.

One promising candidate for new drug development is the COL1A2 protein. COL1A2 was found to be involved in a variety of physiological processes, including cell proliferation, differentiation, migration and extracellular matrix formation. COL1A2 also plays an important role in many diseases, such as inflammation, tissue damage and tumors. Therefore, studying the pharmacological effects of COL1A2 and its potential as a drug target are of great significance for the treatment of fibrous tissue and chronic pain.

Biological functions of COL1A2

COL1A2 is an important collagen protein that is expressed in a variety of tissues. Its main function is to participate in the synthesis and structure of collagen. COL1A2 is made of

Protein Name: Collagen Type I Alpha 2 Chain

Functions: Type I collagen is a member of group I collagen (fibrillar forming collagen)

More Common Targets

COL1A2-AS1 | COL20A1 | COL21A1 | COL22A1 | COL23A1 | COL24A1 | COL25A1 | COL26A1 | COL27A1 | COL28A1 | COL2A1 | COL3A1 | COL4A1 | COL4A2 | COL4A2-AS1 | COL4A3 | COL4A4 | COL4A5 | COL4A6 | COL5A1 | COL5A2 | COL5A3 | COL6A1 | COL6A2 | COL6A3 | COL6A4P1 | COL6A4P2 | COL6A5 | COL6A6 | COL7A1 | COL8A1 | COL8A2 | COL9A1 | COL9A2 | COL9A3 | COLCA1 | COLEC10 | COLEC11 | COLEC12 | COLGALT1 | COLGALT2 | Colipase-Lipase complex | Collagen | Collagen alpha-1(I) chain | Collagen I | Collagen IV | Collagen IX | Collagen V | Collagen VI | Collagen VIII | Collagen XI | Collagenase | Colony-stimulating factor | COLQ | COMETT | COMMD1 | COMMD10 | COMMD2 | COMMD3 | COMMD3-BMI1 | COMMD4 | COMMD5 | COMMD6 | COMMD7 | COMMD8 | COMMD9 | COMP | Complement Complex | Complement component 1q | Complement component C1 | Complement component C8 | COMT | COMTD1 | Condensin complex | Condensin-2 complex | Conserved oligomeric Golgi complex | COP1 | COP9 signalosome complex | COPA | COPB1 | COPB2 | COPB2-DT | COPE | COPG1 | COPG2 | COPG2IT1 | COPRS | COPS2 | COPS3 | COPS4 | COPS5 | COPS6 | COPS7A | COPS7B | COPS8 | COPS8P3 | COPS9 | COPZ1 | COPZ2 | COQ10A