COMMD7: A Protein Involved in Cell Signaling and Disease (G149951)

Target Name: COMMD7

NCBI ID: G149951

COMMD7: A Protein Involved in Cell Signaling and Disease

COMMD7 (COMD7_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and pancreas. It is a member of the COMD7 family, which includes proteins that are involved in various cellular processes, including cell signaling, DNA replication, and inflammation.

One of the key functions of COMMD7 is its role in the regulation of cellular signaling pathways. COMMD7 has been shown to play a role in the development and maintenance of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In addition to its role in cellular signaling, COMMD7 is also a potential drug target. Researchers have identified several potential drugs that can inhibit COMMD7 activity and are currently in the process of testing these drugs in clinical trials. If these drugs are successful in treating these diseases, they could be a valuable new treatment option for patients.

COMMD7 is also a potential biomarker for several diseases. Its expression has been shown to be elevated in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This suggests that COMMD7 may be a useful diagnostic tool for these diseases, and that its levels can be used to monitor the effectiveness of potential treatments.

In conclusion, COMMD7 is a protein that is expressed in various tissues of the human body and is involved in the regulation of cellular signaling pathways. It is also a potential drug target and biomarker for several diseases. Further research is needed to fully understand its role in these processes and to develop new treatments for diseases that are currently untreated.

Protein Name: COMM Domain Containing 7

Functions: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Associates with the NF-kappa-B complex and suppresses its transcriptional activity (PubMed:15799966)

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