Coenzyme Q10 as A Drug Target (G80219)

Target Name: COQ10B

NCBI ID: G80219

Coenzyme Q10 as A Drug Target

Coenzyme Q10 (COQ) is a ubiquitous molecule that is found in every cell of the body. It is a key energy-producing enzyme that is involved in the production of energy from food. In addition to its role in energy production, COQ has also been shown to have a variety of other functions in the body, including maintaining cellular health and protecting against oxidative stress.

One of the newer findings about COQ is its potential as a drug target. Several studies have shown that COQ can be modulated by drugs in order to improve cellular health and protect against oxidative stress. This has led many researchers to investigate the possibility of using COQ as a drug therapy for a variety of conditions.

One of the first drugs to be developed as a potential COQ inhibitor was Q10-052. This drug was developed by researchers at the University of California, San Diego and is currently being tested in clinical trials for the treatment of heart failure. In these trials, Q10-052 has been shown to improve cellular health and reduce oxidative stress in heart failure patients.

Another potential COQ inhibitor is COQ-28. This compound was developed by researchers at the University of Michigan and has also been shown to improve cellular health and reduce oxidative stress in a variety of cells, including cancer cells.

In addition to these drugs, researchers are also exploring the use of COQ as a biomarker for certain diseases. By measuring the levels of COQ in cells, researchers can gain insight into the level of cellular stress and oxidative stress that is present. This has led to the possibility of using COQ as a diagnostic tool for diseases such as cancer, heart disease, and neurological disorders.

Overall, the potential of COQ as a drug target is an exciting area of research that has the potential to improve the lives of many people. While more research is needed, the studies that have been done so far suggest that COQ is a promising molecule for the development of new drugs.

Protein Name: Coenzyme Q10B

Functions: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity)

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