Target Name: CPAMD8
NCBI ID: G27151
Other Name(s): CPAMD8 variant 1 | ASGD8 | C3 and PZP like alpha-2-macroglobulin domain containing 8, transcript variant 1 | K-CAP | CPMD8_HUMAN | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 | C3 and PZP like alpha-2-macroglobulin domain containing 8 | alpha-2 macroglobulin family protein VIP | KIAA1283 | VIP | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 precursor

Unlocking the Potential of CPAMD8: A Drug Target and Biomarker

Introduction

C Paladin 8 (CPAMD8) is a potential drug target and biomarker. As a glycoprotein, it is expressed in a variety of tumor cells and can be used for tumor diagnosis, treatment and prognosis. This article will explore the characteristics, mechanism of action and potential of CPAMD8 as a drug target or biomarker.

Features of CPAMD8

CPAMD8 is a glycoprotein composed of two major subunits: N-terminal 伪-helix and C-terminal 尾-sheet. It has a highly conserved amino acid sequence and is expressed in a variety of tumor cells. The expression level of CPAMD8 was positively correlated with tumor aggressiveness and growth rate, suggesting that it may serve as a valuable biomarker. In addition, CPAMD8 is also associated with tumor cell evasion from the immune surveillance system (TAS), which provides the possibility of it being a drug target.

CPAMD8鈥檚 mechanism of action

CPAMD8, as a glycoprotein, has multiple biological functions in tumor cells. First, CPAMD8 can serve as a glycoprotein receptor on the tumor cell membrane and bind to ligands on the surface of tumor cells, leading to tumor cell growth, invasion and metastasis. Secondly, CPAMD8 can regulate the immune evasion of tumor cells, allowing tumor cells to evade the immune surveillance system by inhibiting the activation and proliferation of T cells. Finally, CPAMD8 can also participate in the growth and regeneration of tumor cells, thus providing support for tumor cell invasion and metastasis.

Drug target potential of CPAMD8

As a glycoprotein, CPAMD8 has multiple drug target potentials. First, CPAMD8 can be used as a target for anti-tumor drugs because its expression level is positively correlated with tumor aggressiveness and growth rate. Secondly, CPAMD8 can serve as a target for immune evasion of tumor cells because its ability to inhibit T cell activation and proliferation can increase the sensitivity of tumor cells to immunotherapy. Finally, CPAMD8 can also serve as a target for tumor cell growth and regeneration because its expression level can reflect the growth and regeneration capabilities of tumor cells.

Biomarker potential of CPAMD8

As a glycoprotein, CPAMD8 can also be used as a tumor biomarker. Its expression level is positively correlated with tumor aggressiveness and growth rate, which makes it highly sensitive and specific as a tumor biomarker. In addition, CPAMD8 can also serve as a biomarker for tumor cells to evade the immune surveillance system because its ability to inhibit T cell activation and proliferation can increase the sensitivity of tumor cells to immunotherapy.

in conclusion

As a glycoprotein, CPAMD8 has multiple biological functions and potential as a drug target or biomarker. With further research, CPAMD8 is expected to become an important tumor treatment target or biomarker, bringing more hope to the treatment of tumor patients.

Protein Name: C3 And PZP Like Alpha-2-macroglobulin Domain Containing 8

More Common Targets

CPB1 | CPB2 | CPB2-AS1 | CPD | CPE | CPEB1 | CPEB1-AS1 | CPEB2 | CPEB2-DT | CPEB3 | CPEB4 | CPED1 | CPHL1P | CPLANE1 | CPLANE2 | CPLX1 | CPLX2 | CPLX3 | CPLX4 | CPM | CPN1 | CPN2 | CPNE1 | CPNE2 | CPNE3 | CPNE4 | CPNE5 | CPNE6 | CPNE7 | CPNE8 | CPNE9 | CPOX | CPPED1 | CPQ | CPS1 | CPS1-IT1 | CPSF1 | CPSF1P1 | CPSF2 | CPSF3 | CPSF4 | CPSF4L | CPSF6 | CPSF7 | CPT1A | CPT1B | CPT1C | CPT2 | CPTP | CPVL | CPVL-AS2 | CPXCR1 | CPXM1 | CPXM2 | CPZ | CR1 | CR1L | CR2 | CRABP1 | CRABP2 | CRACD | CRACDL | CRACR2A | CRACR2B | CRADD | CRADD-AS1 | CRAMP1 | CRAT | CRAT37 | CRB1 | CRB2 | CRB3 | CRBN | CRCP | CRCT1 | Creatine Kinase | CREB1 | CREB3 | CREB3L1 | CREB3L2 | CREB3L3 | CREB3L4 | CREB5 | CREBBP | CREBL2 | CREBRF | CREBZF | CREG1 | CREG2 | CRELD1 | CRELD2 | CREM | CRH | CRHBP | CRHR1 | CRHR2 | CRIM1 | CRIM1-DT | CRIP1 | CRIP1P1