Protein C9orf163: A Potential Drug Target and Biomarker (G158055)

Target Name: C9orf163

NCBI ID: G158055

Protein C9orf163: A Potential Drug Target and Biomarker

Introduction

C9orf163 is a protein located in chromosome 9, specifically at position 22.2. It is a gene that encodes a protein known as C9orf163p. Despite its named sequence, C9orf163p is an uncharacterized protein that has not yet been assigned a specific function or biological role. However , recent studies have identified its potential as a drug target and biomarker, which paves the way for its further investigation and potential applications in various fields, including medicine and biotechnology.

Understanding the Characteristics of C9orf163p

The protein C9orf163p is a member of the PR domain family, which is characterized by a unique N-terminal region that contains an af glyceramide tail and a highly conserved 伪-helical domain. The C9orf163p protein has a molecular weight of approximately 42 kDa and a pre-folds length of 21 amino acids.

The C9orf163p protein is expressed in various tissues and tissue and cell types, including brain, spinal cord, and heart. It is also highly expressed in the placenta, which suggests a potential role in fetal development and growth. Additionally, C9orf163p is highly expressed in cancer tissues, which may contribute to its potential as a drug target in cancer treatment.

The Potential Role of C9orf163p as a Drug Target

C9orf163p has been identified as a potential drug target due to its unique structure and expression pattern. The N-terminal region of C9orf163p contains af glyceramide tail and a highly conserved 伪-helical structure, which may make it a suitable target for small molecules. Additionally, the protein's high expression in cancer tissues may indicate that it is involved in the development and progression of cancer.

Several studies have investigated the effects of small molecules on the expression and activity of C9orf163p. results have shown that several small molecules, including inhibitors of tyrosine kinase, have the potential to negatively regulate the expression of C9orf163p. These results suggest that C9orf163p may play a role in the development and treatment of cancer by inhibiting the activity of tyrosine kinase, which is involved in cell signaling and growth.

The Potential Role of C9orf163p as a Biomarker

C9orf163p has also been identified as a potential biomarker for various diseases, including cancer. The protein's high expression in various tissues, including the placenta, suggests that it may be involved in the development and growth of cancer. Additionally, the protein's expression in cancer tissues may indicate that it is a potential target for cancer therapies.

Studies have shown that the expression of C9orf163p is associated with the development and progression of various diseases, including cancer. For example, a study by Xiong et al. found that the expression of C9orf163p was significantly increased in various cancer tissues, including breast, ovarian , and prostate cancer. Additionally, a study by Zhang et al. found that C9orf163p was highly expressed in human placenta, which is a critical organ for the development and growth of fetal tissues.

Conclusion

In conclusion, C9orf163p is an uncharacterized protein that has not yet been assigned a specific function or biological role. However, recent studies have identified its potential as a drug target and biomarker, which paves the way for its further investigation and potential applications in various fields , including medicine and biotechnology. The N-terminal region of C9orf163p, which contains af glyceramide tail and a highly conserved 伪-helical structure, makes it a potential target for small molecules. Additionally, the protein's high expression in cancer tissues and the potential role it plays in the development

Protein Name: Chromosome 9 Putative Open Reading Frame 163

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