Bloom Syndrome
About the Disease
Bloom Syndrome, also known as bloom-torre-machacek syndrome, is related to microcephaly, growth restriction, and increased sister chromatid exchange 2 and fanconi anemia, complementation group j. An important gene associated with Bloom Syndrome is BLM (BLM RecQ Like Helicase), and among its related pathways/superpathways are Disease and "Cell Cycle, Mitotic". Affiliated tissues include skin, t cells and myeloid, and related phenotypes are intrauterine growth retardation and severe postnatal growth retardation
Common Targets / Biomarkers
G116028 | G5313 | G100313773 | G641 | G80010 | G5315
Other Diseases
Blue Nevus | Blue Rubber Bleb Nevus Syndrome | Bone Giant Cell Tumor | Bone Marrow Necrosis | Borderline Personality Disorder | Borjeson-Forssman-Lehmann Syndrome | Botulism | Brachial Plexus Neuropathy | Brachydactyly | Branchiootorenal Syndrome | Brenner Tumor | Bronchiectasis | Bronchiolitis | Bronchitis | Bronchitis, Chronic | Brooke-Spiegler Syndrome | Bruck Syndrome | Brugada Syndrome 1 | Budd-Chiari Syndrome | Bullous Pemphigoid | Burn-McKeown Syndrome | Bursitis | C3 Glomerulonephritis | C3 Glomerulopathy | Cabezas Syndrome | Calcium Pyrophosphate Deposition Disease | Campomelic Dysplasia | Camptocormia | Camurati-Engelmann Disease | Canavan Disease | Cancer, Bladder | Cancer, Brain | Cancer, Breast | Cancer, Colon | Cancer, Kidney | Cancer, Lung | Cancer, Prostate | Cancer, Skin | Cantu Syndrome | Carbohydrate Metabolism Disorders | Carbonic Anhydrase VA Deficiency | Carcinoid Syndrome | Carcinoid Tumor | Carcinoma In Situ | Carcinoma, Merkel Cell | Carcinoma, Signet Ring Cell | Carcinoma, Small Cell | Carcinoma, Squamous Cell | Carcinoma, Transitional Cell | Cardiac Arrest | Cardiac Sarcoidosis | Cardiofaciocutaneous Syndrome | Cardiomyopathy, Dilated, 1L | Cardiomyopathy, Hypertrophic | Cardiomyopathy, Restrictive | Cardiospondylocarpofacial Syndrome | Carey-Fineman-Ziter Syndrome | Carney Triad | Carney-Stratakis Syndrome | Carotid Artery Disease | Carpal Tunnel Syndrome | Cartilage Disorders | Castleman Disease | Cat Eye Syndrome | Cataplexy | Cataract | Cavitary Optic Disc Anomalies | CDKL5 Deficiency Disorder | CEDNIK Syndrome | Celiac Disease | Cellulitis | Cenani-Lenz Syndactyly Syndrome | Central Core Disease | Central Pain Syndrome | Central Retinal Artery Occlusion | Centronuclear Myopathy | Cerebellar Ataxia, Cayman Type | Cerebellofaciodental Syndrome | Cerebral Amyloid Angiopathy | Cerebral Cavernous Malformations | Cerebrotendinous Xanthomatosis | Cerebrovascular Disorders | Cervical Dystonia | Cervicitis | Chanarin-Dorfman Syndrome | Charcot-Marie-Tooth Disease | Charcot-Marie-Tooth Disease Axonal Type 2N | Charcot-Marie-Tooth Disease Type 2D | Charcot-Marie-Tooth Disease Type 2E | Charcot-Marie-Tooth Disease Type 2T | Charcot-Marie-Tooth Disease Type 3 | Charcot-Marie-Tooth Disease Type 4 | Charcot-Marie-Tooth Disease Type 4B1 | Charcot-Marie-Tooth Disease Type 4D | Charcot-Marie-Tooth Disease Type 4E | Charcot-Marie-Tooth Disease, Type 1A | Charcot-Marie-Tooth Disease, Type 2 | Charcot-Marie-Tooth Disease, Type 2A | Charcot-Marie-Tooth Disease, Type 2C | CHARGE Syndrome | Cheilitis | Chitayat Syndrome | Chloridorrhea, Congenital | Cholangiocarcinoma | Cholangitis | Cholecystitis | Cholelithiasis | Cholera | Cholestasis | Cholestasis, Intrahepatic | Cholesteryl Ester Storage Disease | Chondrodysplasia Punctata | Chondrodysplasia Punctata 1, X-linked Recessive | Chondrodysplasia Punctata 2, X-linked Dominant | Chondroma | Chondromyxoid Fibroma | Chondrosarcoma | CHOPS Syndrome | Chordoid Glioma | Chordoma | Chorea | Chorea-acanthocytosis | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Choriocarcinoma | Chorioretinitis | Choroideremia | Choroiditis | Christianson Syndrome | Chromosome 16p11.2 Deletion Syndrome | Chromosome 17q21.31 Deletion Syndrome | Chromosome 5q Deletion Syndrome | Chromosome 8q21.11 Deletion Syndrome | Chromosome 9q34.3 Deletion Syndrome | Chronic Beryllium Disease | Chronic Enteropathy Associated With SLCO2A1 Gene | Chronic Granulomatous Disease | Chronic Granulomatous Disease, X-linked | Chronic Idiopathic Myelofibrosis | Chronic Inflammatory Demyelinating Polyneuropathy | Chronic Kidney Disease | Chronic Leukemia | Chronic Lymphocytic Leukemia | Chronic Mucocutaneous Candidiasis | Chronic Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Chronic Neutrophilic Leukemia | Chronic Periodontitis | Chronic Thromboembolic Pulmonary Hypertension | Chudley-McCullough Syndrome | Chylomicron Retention Disease | Chylothorax, Congenital | Cirrhosis | Citrullinemia | Cleidocranial Dysplasia | Clouston Hidrotic Ectodermal Dysplasia | Cluster Headache | COACH Syndrome | Cockayne Syndrome | Coenzyme Q10 Deficiency | Coffin-Lowry Syndrome | Coffin-Siris Syndrome | Cohen Syndrome | Cold Agglutinin Disease | Cold-induced Sweating Syndrome | Cole-Carpenter Syndrome | Colitis | Colitis, Collagenous | Colitis, Lymphocytic | Colitis, Microscopic | Coloboma | Colon Adenoma | Colorectal Adenoma | Coma | Combined Deficiency Of Factor V And Factor VIII | Combined Malonic And Methylmalonic Acidemia | Combined Pituitary Hormone Deficiency | Common Cold | Common Variable Immunodeficiency | Communication Disorders | Compartment Syndrome | Conduct Disorder | Cone Dystrophy | Congenital Absence Of Vas Deferens | Congenital Adrenal Hyperplasia | Congenital Adrenal Hyperplasia 1 | Congenital Afibrinogenemia | Congenital Aniridia | Congenital Bilateral Absence Of Vas Deferens | Congenital Bile Acid Synthesis Defect | Congenital Central Hypoventilation Syndrome | Congenital Diaphragmatic Hernia | Congenital Disorders Of Glycosylation | Congenital Disorders Of Glycosylation Type II | Congenital Dyserythropoietic Anemia | Congenital Dyserythropoietic Anemia Type 1 | Congenital Dyserythropoietic Anemia Type 4 | Congenital Dysfibrinogenemia | Congenital Fiber-type Disproportion Myopathy | Congenital Generalized Lipodystrophy | Congenital Heart Block | Congenital Heart Defects | Congenital Hemolytic Anemia | Congenital Hereditary Endothelial Dystrophy Type II | Congenital Hypofibrinogenemia | Congenital Ichthyosiform Erythroderma | Congenital Lipoid Adrenal Hyperplasia | Congenital Mirror Movements | Congenital Muscular Dystrophy | Congenital Myasthenic Syndrome | Congenital Myopathy | Congenital Nephrotic Syndrome | Congenital Nystagmus | Congenital Poikiloderma | Congenital Primary Aphakia | Congenital Sodium Diarrhea | Congenital Stationary Night Blindness | Congenital Stromal Corneal Dystrophy | Congenital Torticollis | Congenital Tufting Enteropathy | Congestive Heart Failure | Conjunctivitis | Conjunctivitis, Allergic | Connective Tissue Disorders | Constipation | Contact Dermatitis | Corneal Dystrophies, Hereditary | Corneal Dystrophy | Corneal Dystrophy And Perceptive Deafness | Corneal Edema | Corneal Neovascularization | Corneal Ulcer | Cornelia De Lange Syndrome | Coronary Artery Disease | Coronary Heart Disease | Coronary Restenosis | Corticobasal Syndrome | Costello Syndrome | Cousin Syndrome | Cramp Fasciculation Syndrome | Cranial Nerve Disease | Cranioectodermal Dysplasia | Craniofacial Dysostosis | Craniofrontonasal Syndrome | Craniolenticulosutural Dysplasia | Craniometaphyseal Dysplasia | Craniopharyngioma | Craniosynostosis | Creatine Deficiency Syndrome | Creatine Deficiency Syndrome Due To AGAT Deficiency | CREST Syndrome | Cri-du-chat Syndrome | Crigler-Najjar Syndrome | Crimean-Congo Hemorrhagic Fever | Cryopyrin-associated Periodic Syndromes | Cryptococcal Meningitis | Cryptorchidism | Cryptosporidiosis | Currarino Syndrome | Cushing Syndrome | Cutaneous Angiosarcoma | Cutaneous Lupus Erythematosus | Cutaneous Mastocytosis | Cutaneous T-cell Lymphoma | Cutis Laxa | Cyclic Vomiting Syndrome | Cyst | Cysticercosis | Cystinosis | Cystinuria | Cystitis | Cystitis, Interstitial | D-2-Hydroxyglutaric Aciduria | Danon Disease | Delayed Sleep Phase Syndrome | Delirium | Dementia | Dementia, Vascular | DEND Syndrome | Dengue Hemorrhagic Fever | Dengue Shock Syndrome | Dent Disease | Dental Caries | Dentinogenesis Imperfecta | Depression | Dermatitis | Dermatitis Herpetiformis | Dermatofibrosarcoma | Dermatomyositis | Desbuquois Syndrome | Desmosterolosis | Diabetes | Diabetes Gestational | Diabetes Insipidus | Diabetes Insipidus, Nephrogenic | Diabetes Insipidus, Neurogenic | Diabetes Mellitus, Transient Neonatal | Diabetes Type 1 | Diabetes Type 2 | Diabetic Encephalopathy | Diabetic Macular Edema | Diabetic Nephropathy | Diabetic Neuropathy | Diamond-Blackfan Anemia | Diarrhea | Diastrophic Dysplasia | DICER1 Syndrome | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Diffuse Intrinsic Pontine Glioma | Diffuse Mesangial Sclerosis | Diffuse Palmoplantar Keratoderma | DiGeorge Syndrome | Discoid Lupus Erythematosus | Disseminated Intravascular Coagulation | Disseminated Superficial Actinic Porokeratosis | Distal Myopathy | Distal Myopathy 2 | Distal Spinal Muscular Atrophy | Diverticulitis | DNA Ligase IV Deficiency | DOCK8 Immunodeficiency Syndrome | Dominant Optic Atrophy | Donnai-Barrow Syndrome | Double Outlet Right Ventricle | Dowling-Degos Disease | Down Syndrome | DRESS Syndrome | Duane Retraction Syndrome | Dubin-Johnson Syndrome | Duchenne Muscular Dystrophy | Duodenal Atresia | Dupuytren Disease | Dwarfism | Dyggve-Melchior-Clausen Disease | Dysequilibrium Syndrome | Dysferlinopathy | Dysfibrinogenemia | Dyskeratosis Congenita | Dyslexia | Dyslipidemia | Dysmorphophobia | Dysplastic Nevus | Dysthymia | Dystonia | Dystonia Musculorum Deformans | Dystonia-parkinsonism, X-linked | Dystrophy, Cone-rod | Early Infantile Epileptic Encephalopathy | Early Infantile Epileptic Encephalopathy 1 | Early Infantile Epileptic Encephalopathy 13 | Early Infantile Epileptic Encephalopathy 28 | Early Infantile Epileptic Encephalopathy 4 | Eating Disorder | Ebstein Anomaly | Eccrine Porocarcinoma | Echinococcosis | Eclampsia | Ectodermal Dysplasia | Ectopia Lentis, Isolated, Autosomal Recessive | Ectrodactyly | Eczema | Ehlers-Danlos Syndrome | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Eiken Syndrome | Ellis-Van Creveld Syndrome | Emery-Dreifuss Muscular Dystrophy | Empyema | Encephalitis | Encephalitis, Tick-borne | Encephalocele | Encephalopathy | Encephalopathy, Ethylmalonic | Encephalopathy, Glycine | Encephalopathy, Hepatic | Endocarditis | Endometrial Hyperplasia | Endometriosis | Endometritis | Endophthalmitis | Enhanced S-cone Syndrome | Enlarged Vestibular Aqueduct | Enterocolitis, Necrotizing | Eosinophilia | Eosinophilic Asthma | Ependymoma | Epicondylitis | Epidermal Nevus Syndrome | Epidermodysplasia Verruciformis | Epidermolysis Bullosa | Epidermolysis Bullosa Acquisita | Epidermolysis Bullosa Dystrophica | Epidermolysis Bullosa Simplex | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Epidermolysis Bullosa Simplex, Generalized | Epidermolysis Bullosa Simplex, Localized | Epidermolytic Hyperkeratosis | Epidermolytic Ichthyosis, Annular | Epidermolytic Palmoplantar Keratoderma | Epilepsy | Epilepsy Of Infancy With Migrating Focal Seizures | Epilepsy, Generalized
