Dentinogenesis Imperfecta
About the Disease
Dentinogenesis Imperfecta, also known as hereditary opalescent dentin, is related to dentinogenesis imperfecta 1 and osteogenesis imperfecta, type v. An important gene associated with Dentinogenesis Imperfecta is DSPP (Dentin Sialophosphoprotein), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Collagen chain trimerization. Affiliated tissues include Tooth, bone and skin, and related phenotypes are pulp obliteration and grayish enamel
Common Targets / Biomarkers
G1277 | G1278 | G1834
Other Diseases
Depression | Dermatitis | Dermatitis Herpetiformis | Dermatofibrosarcoma | Dermatomyositis | Desbuquois Syndrome | Desmosterolosis | Diabetes | Diabetes Gestational | Diabetes Insipidus | Diabetes Insipidus, Nephrogenic | Diabetes Insipidus, Neurogenic | Diabetes Mellitus, Transient Neonatal | Diabetes Type 1 | Diabetes Type 2 | Diabetic Encephalopathy | Diabetic Macular Edema | Diabetic Nephropathy | Diabetic Neuropathy | Diamond-Blackfan Anemia | Diarrhea | Diastrophic Dysplasia | DICER1 Syndrome | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Diffuse Intrinsic Pontine Glioma | Diffuse Mesangial Sclerosis | Diffuse Palmoplantar Keratoderma | DiGeorge Syndrome | Discoid Lupus Erythematosus | Disseminated Intravascular Coagulation | Disseminated Superficial Actinic Porokeratosis | Distal Myopathy | Distal Myopathy 2 | Distal Spinal Muscular Atrophy | Diverticulitis | DNA Ligase IV Deficiency | DOCK8 Immunodeficiency Syndrome | Dominant Optic Atrophy | Donnai-Barrow Syndrome | Double Outlet Right Ventricle | Dowling-Degos Disease | Down Syndrome | DRESS Syndrome | Duane Retraction Syndrome | Dubin-Johnson Syndrome | Duchenne Muscular Dystrophy | Duodenal Atresia | Dupuytren Disease | Dwarfism | Dyggve-Melchior-Clausen Disease | Dysequilibrium Syndrome | Dysferlinopathy | Dysfibrinogenemia | Dyskeratosis Congenita | Dyslexia | Dyslipidemia | Dysmorphophobia | Dysplastic Nevus | Dysthymia | Dystonia | Dystonia Musculorum Deformans | Dystonia-parkinsonism, X-linked | Dystrophy, Cone-rod | Early Infantile Epileptic Encephalopathy | Early Infantile Epileptic Encephalopathy 1 | Early Infantile Epileptic Encephalopathy 13 | Early Infantile Epileptic Encephalopathy 28 | Early Infantile Epileptic Encephalopathy 4 | Eating Disorder | Ebstein Anomaly | Eccrine Porocarcinoma | Echinococcosis | Eclampsia | Ectodermal Dysplasia | Ectopia Lentis, Isolated, Autosomal Recessive | Ectrodactyly | Eczema | Ehlers-Danlos Syndrome | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Eiken Syndrome | Ellis-Van Creveld Syndrome | Emery-Dreifuss Muscular Dystrophy | Empyema | Encephalitis | Encephalitis, Tick-borne | Encephalocele | Encephalopathy | Encephalopathy, Ethylmalonic | Encephalopathy, Glycine | Encephalopathy, Hepatic | Endocarditis | Endometrial Hyperplasia | Endometriosis | Endometritis | Endophthalmitis | Enhanced S-cone Syndrome | Enlarged Vestibular Aqueduct | Enterocolitis, Necrotizing | Eosinophilia | Eosinophilic Asthma | Ependymoma | Epicondylitis | Epidermal Nevus Syndrome | Epidermodysplasia Verruciformis | Epidermolysis Bullosa | Epidermolysis Bullosa Acquisita | Epidermolysis Bullosa Dystrophica | Epidermolysis Bullosa Simplex | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Epidermolysis Bullosa Simplex, Generalized | Epidermolysis Bullosa Simplex, Localized | Epidermolytic Hyperkeratosis | Epidermolytic Ichthyosis, Annular | Epidermolytic Palmoplantar Keratoderma | Epilepsy | Epilepsy Of Infancy With Migrating Focal Seizures | Epilepsy, Generalized | Epiphyseal Chondrodysplasia, Miura Type | Episodic Ataxia | Episodic Ataxia Type 1 | Episodic Ataxia Type 2 | Epithelial-myoepithelial Carcinoma | Epithelioid Hemangioma | Erdheim-Chester Disease | Erectile Dysfunction | Erysipelas | Erythema Multiforme | Erythema Nodosum | Erythematotelangiectatic Rosacea | Erythrokeratodermia Variabilis | Erythromelalgia | Erythropoietic Protoporphyria | Esophageal Adenocarcinoma | Esophageal Motility Disorders | Esophagitis | Essential Fructosuria | Esthesioneuroblastoma | Evans Syndrome | Exfoliative Dermatitis | Exocrine Pancreatic Insufficiency | Exostoses | Exotropia | Extramammary Paget's Disease | Fabry's Disease | Facioscapulohumeral Muscular Dystrophy | Facioscapulohumeral Muscular Dystrophy Type 1 | Facioscapulohumeral Muscular Dystrophy Type 2 | Fahr Disease | Familial Advanced Sleep Phase Syndrome | Familial Cerebral Amyloid Angiopathy | Familial Digital Arthropathy-brachydactyly | Familial Dysautonomia | Familial Episodic Pain Syndrome | Familial Exudative Vitreoretinopathy | Familial Glucocorticoid Deficiency | Familial Hemiplegic Migraine | Familial Hyperaldosteronism | Familial Hypertrophic Cardiomyopathy | Familial Hypobetalipoproteinemia | Familial Isolated Hyperparathyroidism | Familial Mediterranean Fever | Familial Partial Lipodystrophy | Familial Pheochromocytoma-paraganglioma | Familial Retinal Arterial Macroaneurysm | Familial Thoracic Aortic Aneurysm | Fanconi Anemia | Fanconi Syndrome | Farber Disease | Fascioliasis | Fatty Aldehyde Dehydrogenase Deficiency | Feingold Syndrome | Fetal Akinesia Deformation Sequence | Fetal Alcohol Syndrome | Fetal And Neonatal Alloimmune Thrombocytopenia | FG Syndrome | Fibrillation, Atrial | Fibrodysplasia Ossificans Progressiva | Fibromuscular Dysplasia | Fibromyalgia | Fibronectin Glomerulopathy | Fibrosarcoma | Fibrosis | Filariasis | Focal Cortical Dysplasia Type 2 | Focal Dermal Hypoplasia | Focal Facial Dermal Dysplasia | Focal Segmental Glomerulosclerosis | Follicular Dendritic Cell Sarcoma | Fontaine Progeroid Syndrome | Fowler's Syndrome | Frank-ter Haar Syndrome | Frontometaphyseal Dysplasia | Frontotemporal Dementia | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Fuchs Dystrophy | Fuchs Heterochromic Iridocyclitis | Fucosidosis | Fukuyama Congenital Muscular Dystrophy | Fundus Albipunctatus | Galactosemia | Galactosialidosis | Galloway-Mowat Syndrome | Gallstones | Ganglioglioma | Ganglioneuroma | Gangliosidosis | Gangliosidosis, GM1 | GAPO Syndrome | Gardner Syndrome | Gastric Atrophy | Gastritis | Gastritis, Atrophic | Gastroenteritis | Gastroenteritis, Eosinophilic | Gastrointestinal Disorders | Gastroschisis | GATA2 Deficiency | Gaucher Disease | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Genee-Wiedemann Syndrome | Generalized Epilepsy And Paroxysmal Dyskinesia | Generalized Epilepsy With Febrile Seizures Plus | Genitopatellar Syndrome | Gerodermia Osteodysplastica | Gerstmann-Straussler-Scheinker Syndrome | Gestational Trophoblastic Disease | Ghosal Syndrome | Giant Axonal Neuropathy | Giant Cell Arteritis | Giant Cell Glioblastoma | Gigantism | Gilbert Syndrome | Gingivitis | Gitelman Syndrome | Glanzmann Thrombasthenia | Glaucoma | Glaucoma, Congenital | Glaucomatocyclitic Crisis | Glioblastoma | Glioblastoma Multiforme | Glioma | Gliosarcoma | Globozoospermia | Glomerulonephritis | Glomerulonephritis, Membranoproliferative | Glomerulonephritis, Membranous | Glucagonoma | GLUT1 Deficiency Syndrome | Glutaric Aciduria Type 1 | Glutaric Aciduria Type 2 | Glutaric Aciduria Type 3 | Glutathione Synthetase Deficiency | Glycogen Storage Disease | Glycogen Storage Disease Type 0 | Glycogen Storage Disease Type 0, Muscle | Glycogen Storage Disease Type 1 | Glycogen Storage Disease Type 1a | Glycogen Storage Disease Type 1b | Glycogen Storage Disease Type 3 | Glycogen Storage Disease Type 4 | Glycogen Storage Disease Type 5 | Glycogen Storage Disease Type 6 | Glycogen Storage Disease Type 9 | GM2-gangliosidosis AB Variant | Gnathodiaphyseal Dysplasia | GNE Myopathy | Goiter | Goldenhar Syndrome | Gout | Graft-versus-host Disease | Granular Corneal Dystrophy | Granular Corneal Dystrophy Type 1 | Granuloma Annulare | Graves Disease | Gray Platelet Syndrome | Greenberg Dysplasia | Greig Cephalopolysyndactyly Syndrome | Growth Hormone Excess | Guanidinoacetate Methyltransferase Deficiency | Guillain-Barre Syndrome | Guttate Psoriasis | Gynecomastia | Gyrate Atrophy Of The Choroid And Retina | H Syndrome | Haim-Munk Syndrome | Hairy Cell Leukemia | Hamartoma | HANAC Syndrome | Hartnup Disease | Hartsfield Syndrome | Hashimoto Thyroiditis | Headache | Heart Block | Heart Failure | Heart Septal Defects | Heavy Chain Disease | Heimler Syndrome | HELLP Syndrome | Hemangioblastoma | Hemangioendothelioma | Hemangioma | Hemimegalencephaly | Hemochromatosis | Hemochromatosis Type 1 | Hemochromatosis Type 2 | Hemoglobinopathies | Hemolytic Anemia | Hemolytic Uremic Syndrome | Hemolytic Uremic Syndrome, Atypical | Hemophagocytic Lymphohistiocytosis | Hemophilia | Hemorrhage | Hemorrhagic Disorders | Hemorrhoids | Hemosiderosis | Hennekam Lymphangiectasia-lymphedema Syndrome | Hepatic Adenomatosis | Hepatic Steatosis | Hepatic Veno-occlusive Disease | Hepatitis | Hepatitis A | Hepatitis B, Chronic | Hepatitis C, Chronic | Hepatitis D | Hepatitis E | Hepatitis, Alcoholic | Hepatitis, Autoimmune | Hepatitis, Chronic | Hepatoblastoma | Hepatopulmonary Syndrome | Hepatorenal Syndrome | Hereditary Coproporphyria | Hereditary Elliptocytosis | Hereditary Folate Malabsorption | Hereditary Hemorrhagic Telangiectasia | Hereditary Hemorrhagic Telangiectasia Type 2 | Hereditary Mixed Polyposis Syndrome | Hereditary Multiple Exostoses | Hereditary Neuropathy With Liability To Pressure Palsies | Hereditary Pyropoikilocytosis | Hereditary Sensory And Autonomic Neuropathy | Hereditary Sensory Neuropathy Type 1 | Hereditary Spastic Paraplegia | Hereditary Spherocytosis | Hereditary Xerocytosis | Hermansky-Pudlak Syndrome | Hernia, Inguinal | Herpes Genitalis | Herpes Simplex Dermatitis | Heterotopic Ossification | HIBCH Deficiency | Hidradenitis | Hidradenitis Suppurativa | High Molecular Weight Kininogen Deficiency | Histiocytic Sarcoma | Histiocytosis | Hodgkin Lymphoma | Holoprosencephaly | Holt-Oram Syndrome | Homocystinuria | Hoyeraal-Hreidarsson Syndrome | Huntington's Disease | Huntington's Disease-like 2 | HUPRA Syndrome | Hydrocephalus | Hydrocephalus, Normal Pressure | Hydrolethalus Syndrome | Hydronephrosis | Hydrops Fetalis | Hyper IgE Syndrome | Hyperacusis | Hyperammonemia | Hyperandrogenemia | Hyperbilirubinemia, Neonatal | Hypercalcemia | Hypercalciuria | Hypercholesterolemia | Hypercholesterolemia, Familial | Hyperekplexia | Hypereosinophilic Syndrome | Hyperferritinemia-cataract Syndrome | Hyperglycemia | Hyperhomocysteinemia | Hyperinsulinemia | Hyperinsulinemic Hypoglycemia | Hyperinsulinism-hyperammonemia Syndrome | Hyperkeratosis | Hyperlipidemia | Hyperlipidemia Type V | Hyperlipidemia, Familial Combined | Hypermethioninemia | Hypermetropia | Hyperostosis | Hyperoxaluria | Hyperparathyroidism | Hyperparathyroidism, Primary | Hyperparathyroidism, Secondary | Hyperparathyroidism-jaw Tumor Syndrome | Hyperphenylalaninemia | Hyperphosphatasia With Intellectual Disability Syndrome 4
