Diabetic Nephropathy
About the Disease
Microvascular Complications of Diabetes 2, also known as microvascular complications of diabetes, susceptibility to, 2, is related to microvascular complications of diabetes 3 and background diabetic retinopathy. An important gene associated with Microvascular Complications of Diabetes 2 is EPO (Erythropoietin). The drugs Mecobalamin and Hydroxocobalamin have been mentioned in the context of this disorder. Affiliated tissues include kidney, endothelial and retina.
Common Targets / Biomarkers
DPH1 | ACE | LOC105379399 | HFE | Integrin alphavbeta3 (vitronectin) receptor | SSTR2 | BCL2L12 | FGF18 | GSR | SUMO4 | MED13L | CHN2 | INPPL1 | NR3C2 | PHACTR1 | PDE4B | GRM5 | ADPGK | PPARA | LOC102724087 | Integrin alphaMbeta2 (MAC-1) Receptor | MYH9 | NFE2L2 | FN3K | IL13RA1 | UBA1 | Protein kinase C (nonspecified subtype) | FOLR2 | TBC1D5 | NGFR | CYSLTR1 | CFAP61 | NCOR2 | ACE2 | LGALS3 | MDK | NOS1 | WDR73 | ZNF844 | TMPRSS15 | HLA-DQA1 | PDGFRB | SLC12A3 | FFAR1 | IL7 | ZNF595 | ABTB3 | ZNF788P | TXN | EPHX2 | F13A1 | CACNA1S | PKHD1L1 | TTC21B | MTOR | Phosphodiesterase 1 (PDE1) (nonspecified subtype) | MAOA | LPAR1 | EGF | PLA2G4A | MIR449B | AURKB | ME1 | CDK5/p25 | TYR | SLC19A3 | LGSN | PDZK1 | SIGMAR1 | PRKCA | MGLL | IKZF1 | ADIPOQ | AGT | Endothelin-Converting Enzymes (ECE) (nonspecified subtype) | CNR1 | PPARG | NAE1 | mTOR complex 1 | MIR137 | MIR34A | TRPV1 | PARP1 | CASR | NWD2 | IGF1 | CTSS | DNA Topoisomerase II (nonspecified subtype) | MAP3K5 | HMOX2 | TRPC5 | KEAP1 | CCL5 | PGR | CDK5 | ICAM1 | APLNR | GCK | THBS2 | IRS2 | CDKAL1 | UBA3 | DGAT2 | PTGS1 | NAV3 | SLC17A3 | TBC1D9 | SIRT1 | CTSL | CNOT6L | PKLR | SLC22A12 | CPT1A | PDE1C | SMIM13 | CD2AP | HLA-G | ADP-Ribosyl Cyclase/cyclic ADP-Ribose Hydrolase (ADPRC) (nonspecified subtype) | ENG | HDAC5 | ABCG2 | NR3C1 | PIGU | ANKRD36 | LOC101929129 | TXNIP | Transforming growth factor (nonspecified subtype) | MC2R | ACHE | SCNN1D | GALNTL6 | SORCS3 | NOX4 | MLXIPL | KHK | TMOD1 | IL1RL1 | DOCK6 | PPM1E | LOC105375741 | DPP4 | NFATC2 | PDGFD | NR1I2 | CCN2 | CASP8 | SLC1A5 | SOD2 | MRC1 | TNFRSF19 | CCR2 | PPARD | CNTLN | IL17A | ADIPOQ-AS1 | S1PR2 | ADORA2A | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | AVPR2 | PTGS2 | SHROOM3 | PCSK9 | IL17C | INS | PGAM5-KEAP1-NRF2 Complex | TGFA | AKR1B1 | SYN3 | TGFBR1 | FLT1 | ERRFI1 | PTPN1 | BMP8A | PFKFB2 | GPX1 | MAPK3 | CD38 | KRT6B | VCAM1 | SCAF4 | AMP-activated protein kinase alpha1beta1gamma1 | TGM2 | XDH | SUCLG2 | IL15 | INSR | EDNRB | IGSF22 | IAPP | ITGB2 | MTNR1B | ABCB1 | GLO1 | IMPDH1 | ATAD3B | Casein kinase II (CKII) | GIPR | OR6X1 | XRCC3 | AVEN | NR1H4 | MTHFR | CABCOCO1 | C7orf50 | UTS2R | KDM4D | MVK | VDR | PRMT1 | S1PR3 | GCKR | PTPRJ | CLIC1 | MC3R | TPPP2 | C6orf118 | Mitogen-Activated Protein Kinase (nonspecified subtype) | CASP3 | PIK3C2B | SSTR4 | SERPINE1 | ATP10D | CSMD1 | SMYD4 | COL1A2 | PTGER4 | Na+/K+-ATPase (nonspecified subtype) | ZNF875 | TBC1D31 | ADORA3 | MAPK9 | NOS3 | GCLC | ELMO1 | PHOSPHO1 | LRRC31 | PLG | TRPC6 | SH3YL1 | LOC102724768 | PRKCD | SIGIRR | IL10 | TEK | PLXDC2 | Heme Oxygenase (HO) (nonspecified subtype) | KDR | LOC100130698 | PTP4A3 | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | UHRF1 | WFS1 | MED15 | GREM1 | MME | NEDD8-activating enzyme E1 | Phospholipase A2, Cytosolic (nonspecified subtype) | MMP2 | SF1 | CARS1 | GABRR1 | COMMD1 | ANKRD26 | GPR84 | SUCNR1 | IL1A | PDE5A | HDAC4 | ABCC8 | CALCRL | SLC19A2 | HDAC9 | ABCG8 | C4orf51 | Prostanoid TP receptor (nonspecified subtype) | DDIT3 | CAPN1 | FHOD1 | CHUK | TGFB2 | GHR | SLC17A1 | VEGFA | GUCY1A1 | RBL1 | IFNG | IL1B | Transforming growth factor beta (nonspecified subtype) | F5 | SIK2 | LINC02544 | PDE1B | THBS2-AS1 | NOS2 | PTH | TLR9 | PRKCB | PKM | HIPK2 | PTBP3 | IL6 | ERBB4 | TXNRD1 | ZNF365 | NOX5 | STX18 | ANO9 | GAA | NBPF20 | LPAR4 | PTPRB | NOX3 | FGF1 | SLC5A1 | AGTR1 | GPM6A | Ikzf1 | CNTNAP2 | NRXN2 | QDPR | CCR5 | Integrin alphavbeta6 receptor | SLC2A1 | OLR1 | SMPD3 | APOA1 | ENPP1 | SLC2A1-DT | SERPINF2 | CARMIL1 | SLC34A1 | MIR146A | UMOD | ACACB | SSTR5 | NAMPT | GPX4 | NOX1 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | NEFH | CDK8 | MAPK10 | HLA-DPB1 | TSPYL2 | MC4R | APP | NLRP3 Inflammasome | NPAS2 | IL4 | JAK2 | PLA2R1 | TMEM176A | AGER | CD47 | HPSE | GPR158 | APOL1 | JAK3 | MSR1 | DRD3 | CASP1 | JAML | APOE | AGTR2 | EREG | JAK1 | ECE1 | IKZF2 | ZNF197 | HMGB1 | ABCC1 | FTO | NADPH Oxidase Complex | LRP2 | PLA2G7 | NLRP3 | SLC2A9 | CXCL8 | CCL2 | NF-kappaB (NFkB) | CRBN | Nitric oxide synthase (NOS) (nonspecified subtype) | IL13 | Integrin alphavbeta1 | GLP1R | CCDC14 | DEFB1 | GMFB | BCL2 | F2R | FIG4 | NME7 | XRCC1 | UBR7 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | LOC105370003 | SLC2A2 | DEDD2 | CYP11B2 | PIP4K2A | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | alpha-Amylase (nonspecified subtype) | DDAH2 | TNFRSF14 | TSBP1 | MIR9-3 | LINC01800 | IL18 | ASAP1 | NADPH Oxidase (nonspecified subtype) | TGFB3 | TRPC1 | LRP8 | PRKCE | LOC105378977 | KIT | GPD1L | ANPEP | HMOX1 | Soluble guanylyl cyclase | SCN5A | Mitogen-activated protein kinase (JNK) (nonspecified subtype) | LOC102723341 | TCF7L2 | PDE1A | PRCD | REN | GPAT4 | AOC3 | COL4A4 | CPTP | KCNH7 | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | RHOA | SOD1 | TGFB1 | LY96 | Superoxide dismutase (SOD) (nonspecified subtype) | RASSF2 | CMA1 | Vasopressin V1 Receptor (nonspecified subtype) | BSND | POLR3GL | UNC93A | TLR4 | PDE4D | UCP2 | GAS6 | Phosphodiesterase (nonspecified subtype) | ZNF20 | YAP1 | Glutathione peroxidase (nonspecified subtype) | CASC15 | EDNRA | GCGR | HIF1A | ITPR1 | B9D2 | ECE2 | mu-Calpain (calpain 1) | Transforming growth factor (TGF)-beta receptor (nonspecified subtype) | CAT | CD274 | BTK | PLEKHH2 | ITGAM | CYBA | MYNN | ITGA6 | KRT32 | LCAT | CDK19 | AVPR1A | SLC22A11 | KLF4 | SLC5A2 | TNF | SLC27A3 | GPBAR1 | TBXAS1 | SFT2D1 | RNLS | PPP4R1 | PVT1 | ADAM10 | RPTOR | TRIM37 | SERPINF1 | FFAR4 | SREBF1 | TEX101 | IL33 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | UNC13B | CASP7 | ADCY10 | CSF1R | MGP
Other Diseases
Diabetic Neuropathy | Diamond-Blackfan Anemia | Diarrhea | Diastrophic Dysplasia | DICER1 Syndrome | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Diffuse Intrinsic Pontine Glioma | Diffuse Mesangial Sclerosis | Diffuse Palmoplantar Keratoderma | DiGeorge Syndrome | Discoid Lupus Erythematosus | Disseminated Intravascular Coagulation | Disseminated Superficial Actinic Porokeratosis | Distal Myopathy | Distal Myopathy 2 | Distal Spinal Muscular Atrophy | Diverticulitis | DNA Ligase IV Deficiency | DOCK8 Immunodeficiency Syndrome | Dominant Optic Atrophy | Donnai-Barrow Syndrome | Double Outlet Right Ventricle | Dowling-Degos Disease | Down Syndrome | DRESS Syndrome | Duane Retraction Syndrome | Dubin-Johnson Syndrome | Duchenne Muscular Dystrophy | Duodenal Atresia | Dupuytren Disease | Dwarfism | Dyggve-Melchior-Clausen Disease | Dysequilibrium Syndrome | Dysferlinopathy | Dysfibrinogenemia | Dyskeratosis Congenita | Dyslexia | Dyslipidemia | Dysmorphophobia | Dysplastic Nevus | Dysthymia | Dystonia | Dystonia Musculorum Deformans | Dystonia-parkinsonism, X-linked | Dystrophy, Cone-rod | Early Infantile Epileptic Encephalopathy | Early Infantile Epileptic Encephalopathy 1 | Early Infantile Epileptic Encephalopathy 13 | Early Infantile Epileptic Encephalopathy 28 | Early Infantile Epileptic Encephalopathy 4 | Eating Disorder | Ebstein Anomaly | Eccrine Porocarcinoma | Echinococcosis | Eclampsia | Ectodermal Dysplasia | Ectopia Lentis, Isolated, Autosomal Recessive | Ectrodactyly | Eczema | Ehlers-Danlos Syndrome | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Eiken Syndrome | Ellis-Van Creveld Syndrome | Emery-Dreifuss Muscular Dystrophy | Empyema | Encephalitis | Encephalitis, Tick-borne | Encephalocele | Encephalopathy | Encephalopathy, Ethylmalonic | Encephalopathy, Glycine | Encephalopathy, Hepatic | Endocarditis | Endometrial Hyperplasia | Endometriosis | Endometritis | Endophthalmitis | Enhanced S-cone Syndrome | Enlarged Vestibular Aqueduct | Enterocolitis, Necrotizing | Eosinophilia | Eosinophilic Asthma | Ependymoma | Epicondylitis | Epidermal Nevus Syndrome | Epidermodysplasia Verruciformis | Epidermolysis Bullosa | Epidermolysis Bullosa Acquisita | Epidermolysis Bullosa Dystrophica | Epidermolysis Bullosa Simplex | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Epidermolysis Bullosa Simplex, Generalized | Epidermolysis Bullosa Simplex, Localized | Epidermolytic Hyperkeratosis | Epidermolytic Ichthyosis, Annular | Epidermolytic Palmoplantar Keratoderma | Epilepsy | Epilepsy Of Infancy With Migrating Focal Seizures | Epilepsy, Generalized | Epiphyseal Chondrodysplasia, Miura Type | Episodic Ataxia | Episodic Ataxia Type 1 | Episodic Ataxia Type 2 | Epithelial-myoepithelial Carcinoma | Epithelioid Hemangioma | Erdheim-Chester Disease | Erectile Dysfunction | Erysipelas | Erythema Multiforme | Erythema Nodosum | Erythematotelangiectatic Rosacea | Erythrokeratodermia Variabilis | Erythromelalgia | Erythropoietic Protoporphyria | Esophageal Adenocarcinoma | Esophageal Motility Disorders | Esophagitis | Essential Fructosuria | Esthesioneuroblastoma | Evans Syndrome | Exfoliative Dermatitis | Exocrine Pancreatic Insufficiency | Exostoses | Exotropia | Extramammary Paget's Disease | Fabry's Disease | Facioscapulohumeral Muscular Dystrophy | Facioscapulohumeral Muscular Dystrophy Type 1 | Facioscapulohumeral Muscular Dystrophy Type 2 | Fahr Disease | Familial Advanced Sleep Phase Syndrome | Familial Cerebral Amyloid Angiopathy | Familial Digital Arthropathy-brachydactyly | Familial Dysautonomia | Familial Episodic Pain Syndrome | Familial Exudative Vitreoretinopathy | Familial Glucocorticoid Deficiency | Familial Hemiplegic Migraine | Familial Hyperaldosteronism | Familial Hypertrophic Cardiomyopathy | Familial Hypobetalipoproteinemia | Familial Isolated Hyperparathyroidism | Familial Mediterranean Fever | Familial Partial Lipodystrophy | Familial Pheochromocytoma-paraganglioma | Familial Retinal Arterial Macroaneurysm | Familial Thoracic Aortic Aneurysm | Fanconi Anemia | Fanconi Syndrome | Farber Disease | Fascioliasis | Fatty Aldehyde Dehydrogenase Deficiency | Feingold Syndrome | Fetal Akinesia Deformation Sequence | Fetal Alcohol Syndrome | Fetal And Neonatal Alloimmune Thrombocytopenia | FG Syndrome | Fibrillation, Atrial | Fibrodysplasia Ossificans Progressiva | Fibromuscular Dysplasia | Fibromyalgia | Fibronectin Glomerulopathy | Fibrosarcoma | Fibrosis | Filariasis | Focal Cortical Dysplasia Type 2 | Focal Dermal Hypoplasia | Focal Facial Dermal Dysplasia | Focal Segmental Glomerulosclerosis | Follicular Dendritic Cell Sarcoma | Fontaine Progeroid Syndrome | Fowler's Syndrome | Frank-ter Haar Syndrome | Frontometaphyseal Dysplasia | Frontotemporal Dementia | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Fuchs Dystrophy | Fuchs Heterochromic Iridocyclitis | Fucosidosis | Fukuyama Congenital Muscular Dystrophy | Fundus Albipunctatus | Galactosemia | Galactosialidosis | Galloway-Mowat Syndrome | Gallstones | Ganglioglioma | Ganglioneuroma | Gangliosidosis | Gangliosidosis, GM1 | GAPO Syndrome | Gardner Syndrome | Gastric Atrophy | Gastritis | Gastritis, Atrophic | Gastroenteritis | Gastroenteritis, Eosinophilic | Gastrointestinal Disorders | Gastroschisis | GATA2 Deficiency | Gaucher Disease | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Genee-Wiedemann Syndrome | Generalized Epilepsy And Paroxysmal Dyskinesia | Generalized Epilepsy With Febrile Seizures Plus | Genitopatellar Syndrome | Gerodermia Osteodysplastica | Gerstmann-Straussler-Scheinker Syndrome | Gestational Trophoblastic Disease | Ghosal Syndrome | Giant Axonal Neuropathy | Giant Cell Arteritis | Giant Cell Glioblastoma | Gigantism | Gilbert Syndrome | Gingivitis | Gitelman Syndrome | Glanzmann Thrombasthenia | Glaucoma | Glaucoma, Congenital | Glaucomatocyclitic Crisis | Glioblastoma | Glioblastoma Multiforme | Glioma | Gliosarcoma | Globozoospermia | Glomerulonephritis | Glomerulonephritis, Membranoproliferative | Glomerulonephritis, Membranous | Glucagonoma | GLUT1 Deficiency Syndrome | Glutaric Aciduria Type 1 | Glutaric Aciduria Type 2 | Glutaric Aciduria Type 3 | Glutathione Synthetase Deficiency | Glycogen Storage Disease | Glycogen Storage Disease Type 0 | Glycogen Storage Disease Type 0, Muscle | Glycogen Storage Disease Type 1 | Glycogen Storage Disease Type 1a | Glycogen Storage Disease Type 1b | Glycogen Storage Disease Type 3 | Glycogen Storage Disease Type 4 | Glycogen Storage Disease Type 5 | Glycogen Storage Disease Type 6 | Glycogen Storage Disease Type 9 | GM2-gangliosidosis AB Variant | Gnathodiaphyseal Dysplasia | GNE Myopathy | Goiter | Goldenhar Syndrome | Gout | Graft-versus-host Disease | Granular Corneal Dystrophy | Granular Corneal Dystrophy Type 1 | Granuloma Annulare | Graves Disease | Gray Platelet Syndrome | Greenberg Dysplasia | Greig Cephalopolysyndactyly Syndrome | Growth Hormone Excess | Guanidinoacetate Methyltransferase Deficiency | Guillain-Barre Syndrome | Guttate Psoriasis | Gynecomastia | Gyrate Atrophy Of The Choroid And Retina | H Syndrome | Haim-Munk Syndrome | Hairy Cell Leukemia | Hamartoma | HANAC Syndrome | Hartnup Disease | Hartsfield Syndrome | Hashimoto Thyroiditis | Headache | Heart Block | Heart Failure | Heart Septal Defects | Heavy Chain Disease | Heimler Syndrome | HELLP Syndrome | Hemangioblastoma | Hemangioendothelioma | Hemangioma | Hemimegalencephaly | Hemochromatosis | Hemochromatosis Type 1 | Hemochromatosis Type 2 | Hemoglobinopathies | Hemolytic Anemia | Hemolytic Uremic Syndrome | Hemolytic Uremic Syndrome, Atypical | Hemophagocytic Lymphohistiocytosis | Hemophilia | Hemorrhage | Hemorrhagic Disorders | Hemorrhoids | Hemosiderosis | Hennekam Lymphangiectasia-lymphedema Syndrome | Hepatic Adenomatosis | Hepatic Steatosis | Hepatic Veno-occlusive Disease | Hepatitis | Hepatitis A | Hepatitis B, Chronic | Hepatitis C, Chronic | Hepatitis D | Hepatitis E | Hepatitis, Alcoholic | Hepatitis, Autoimmune | Hepatitis, Chronic | Hepatoblastoma | Hepatopulmonary Syndrome | Hepatorenal Syndrome | Hereditary Coproporphyria | Hereditary Elliptocytosis | Hereditary Folate Malabsorption | Hereditary Hemorrhagic Telangiectasia | Hereditary Hemorrhagic Telangiectasia Type 2 | Hereditary Mixed Polyposis Syndrome | Hereditary Multiple Exostoses | Hereditary Neuropathy With Liability To Pressure Palsies | Hereditary Pyropoikilocytosis | Hereditary Sensory And Autonomic Neuropathy | Hereditary Sensory Neuropathy Type 1 | Hereditary Spastic Paraplegia | Hereditary Spherocytosis | Hereditary Xerocytosis | Hermansky-Pudlak Syndrome | Hernia, Inguinal | Herpes Genitalis | Herpes Simplex Dermatitis | Heterotopic Ossification | HIBCH Deficiency | Hidradenitis | Hidradenitis Suppurativa | High Molecular Weight Kininogen Deficiency | Histiocytic Sarcoma | Histiocytosis | Hodgkin Lymphoma | Holoprosencephaly | Holt-Oram Syndrome | Homocystinuria | Hoyeraal-Hreidarsson Syndrome | Huntington's Disease | Huntington's Disease-like 2 | HUPRA Syndrome | Hydrocephalus | Hydrocephalus, Normal Pressure | Hydrolethalus Syndrome | Hydronephrosis | Hydrops Fetalis | Hyper IgE Syndrome | Hyperacusis | Hyperammonemia | Hyperandrogenemia | Hyperbilirubinemia, Neonatal | Hypercalcemia | Hypercalciuria | Hypercholesterolemia | Hypercholesterolemia, Familial | Hyperekplexia | Hypereosinophilic Syndrome | Hyperferritinemia-cataract Syndrome | Hyperglycemia | Hyperhomocysteinemia | Hyperinsulinemia | Hyperinsulinemic Hypoglycemia | Hyperinsulinism-hyperammonemia Syndrome | Hyperkeratosis | Hyperlipidemia | Hyperlipidemia Type V | Hyperlipidemia, Familial Combined | Hypermethioninemia | Hypermetropia | Hyperostosis | Hyperoxaluria | Hyperparathyroidism | Hyperparathyroidism, Primary | Hyperparathyroidism, Secondary | Hyperparathyroidism-jaw Tumor Syndrome | Hyperphenylalaninemia | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Hyperprolactinemia | Hypersensitivity | Hypersensitivity Pneumonitis | Hypersomnia | Hypertelorism | Hypertension | Hypertension, Essential | Hypertension, Portal | Hypertension, Pulmonary | Hypertension, Renal | Hypertension, Renovascular | Hypertensive Nephropathy | Hypertensive Retinopathy | Hyperthermia, Malignant | Hyperthyroidism | Hypertriglyceridemia | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2
