BHLHA15: A Potential Drug Target and Biomarker (G168620)

Target Name: BHLHA15

NCBI ID: G168620

BHLHA15: A Potential Drug Target and Biomarker

The BHLHA15 gene is located on chromosome 15 and is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. The BHLHA15 gene is involved in the regulation of cell growth, differentiation, and survival, and is associated with various diseases, including cancer.

Drug Target Potential

The BHLHA15 gene has been identified as a potential drug target due to its involvement in cell growth and survival. Studies have shown that BHLHA15 plays a role in the regulation of cell cycle progression and has been shown to be involved in the development of various types of cancer, including lung cancer, breast cancer, and colorectal cancer.

In addition, BHLHA15 has also been shown to be involved in the regulation of cell survival and has been linked to the development of neurodegenerative diseases.

Biomarker Potential

BHLHA15 has also been identified as a potential biomarker for various types of cancer, including lung cancer, breast cancer, and colorectal cancer. The expression of BHLHA15 has been shown to be associated with the development of these diseases, and may be a useful diagnostic or predictive marker for these conditions.

Studies have also shown that BHLHA15 has been shown to be involved in the regulation of cell signaling pathways, including the PI3K/Akt signaling pathway. This suggests that BHLHA15 may be a useful target for drugs that are designed to inhibit this pathway.

Conclusion

In conclusion, the BHLHA15 gene has been identified as a potential drug target and biomarker. The involvement of BHLHA15 in cell growth and survival, as well as its association with the development of various types of cancer, makes it a promising target for drug development. Additionally, BHLHA15 has also been shown to be a potential biomarker for these conditions, making it a valuable tool for the diagnosis and prediction of disease. Further research is needed to fully understand the role of BHLHA15 as a drug target and biomarker.

Protein Name: Basic Helix-loop-helix Family Member A15

Functions: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity)

More Common Targets