DSC3: A Drug Target / Disease Biomarker (G1825)

Target Name: DSC3

NCBI ID: G1825

DSC3: A Drug Target / Disease Biomarker

DSC3 is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of cell death and has been linked to a number of diseases, including neurodegenerative disorders, cancer, and autoimmune diseases.

DSC3 is a member of the superfamily of proteins known as theBeclin-1/DIS/PAS (Death-Inducing Signaling Protein) family. These proteins are characterized by the presence of a specific domain called the death-inducing peptide (DIP), which is responsible for triggering cell death.

DSC3 is expressed in a variety of tissues and is involved in a wide range of physiological processes, including cell death, cell proliferation, and tissue repair. It is highly expressed in the brain, where it is involved in the regulation of neurotransmitter release and neurogenesis, as well as in the development and maintenance of neural stem cells.

DSC3 is also expressed in the heart, where it is involved in the regulation of contractility and cardiac function. It is also expressed in the kidneys, where it is involved in the regulation of urine output and blood pressure.

DSC3 has been linked to a number of diseases and disorders, including neurodegenerative disorders, cancer, and autoimmune diseases. For example, studies have shown that DSC3 is highly expressed in the brains of individuals with Alzheimer's disease, and that it is involved in the development of neurodegeneration in these individuals.

In addition, DSC3 has also been linked to the development and progression of cancer. For example, studies have shown that DSC3 is highly expressed in a variety of cancer tissues, and that it is involved in the regulation of cell growth and survival.

DSC3 is also involved in the regulation of tissue repair and regeneration. For example, studies have shown that DSC3 is involved in the regulation of the stem cell proliferation and differentiation, and that it plays a key role in the development of tissue repair and regeneration following injury or disease.

In conclusion, DSC3 is a protein that is expressed in various tissues throughout the body and is involved in a wide range of physiological processes. It is highly expressed in the brain and heart and has been linked to the development and progression of a variety of diseases and disorders, including neurodegenerative disorders, cancer, and autoimmune diseases. Further research is needed to fully understand the role of DSC3 in these processes and to develop new treatments for these diseases.

Protein Name: Desmocollin 3

Functions: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms

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