TSC22D3: A Drug Target / Disease Biomarker (G1831)

Target Name: TSC22D3

NCBI ID: G1831

TSC22D3: A Drug Target / Disease Biomarker

TSC22D3 is a protein that is expressed in the brain and is known for its role in the development and progression of several neurological disorders, including Alzheimer's disease. The protein is composed of 22 amino acid residues and has a calculated molecular weight of 33 kDa.

TSC22D3 is a scaffold protein that is involved in the formation of the endoplasmic reticulum (ER) and is thought to play a role in the regulation of protein synthesis and degradation. The ER is a structure that retrieves and modifies proteins before they are released from the cell. TSC22D3 is known to be involved in the formation of the ER and has been shown to localize to the ER in various cell types.

In addition to its role in the ER, TSC22D3 is also involved in the regulation of protein stability and has been shown to interact with several protein partners, including the protein poly (ADP-ribose) polymerase (PARP). PARP is a enzyme that is involved in the regulation of DNA replication and has been implicated in the development of age-related diseases, including Alzheimer's disease.

TSC22D3 is also involved in the regulation of cellular processes that are important for the survival and survival of neurons, including the regulation of cell death and the maintenance of cellular homeostasis. The protein has been shown to interact with several proteins that are involved in these processes, including the protein Bcl-2. Bcl-2 is a protein that is known to play a role in the regulation of cell death and has been implicated in the development of neurodegenerative diseases.

In conclusion, TSC22D3 is a protein that is involved in several important processes that are necessary for the survival and survival of neurons. The protein is known to play a role in the regulation of protein synthesis and degradation, as well as the regulation of protein stability and cellular processes that are important for the survival and survival of neurons. Further research is needed to fully understand the role of TSC22D3 in the development and progression of neurological disorders, including Alzheimer's disease.

Protein Name: TSC22 Domain Family Member 3

Functions: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11 (PubMed:15031210). In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10 (PubMed:12393603). In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation and thereby NFKB1 DNA-binding activities (PubMed:11468175). In vitro, suppresses AP-1 transcription factor complex DNA-binding activities (By similarity)

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