Target Name: TSPAN13
NCBI ID: G27075
Other Name(s): Transmembrane 4 superfamily member tetraspan NET-6 | TSN13_HUMAN | FLJ22934 | transmembrane 4 superfamily member tetraspan NET-6 | Tspan-13 | Tetraspan NET-6 | Tetraspanin 13 | tetraspanin 13 | tspan-13 | NET6 | Transmembrane 4 superfamily member 13 | NET-6 | transmembrane 4 superfamily member 13 | TM4SF13 | Tetraspanin-13 | tetraspan NET-6

TSPAN13: A Transmembrane 4 Superfamily Member and Potential Drug Target in Neurodegenerative Disorders

Abstract:
TSPAN13, a member of the Transmembrane 4 Superfamily, has been identified as a potential drug target in neurodegenerative diseases. Its unique structure and various functions, including its role in intracellular signaling and its involvement in various cellular processes, make it an attractive target for the development of new therapeutic approaches. This review summarizes the current understanding of TSPAN13, its potential drug targets, and the progress that has been made in research using this protein as a therapeutic approach.

Introduction:
Neurodegenerative diseases are a group of disorders that characterized by the progressive loss of neurons and their associated synapses. These disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease, are the leading causes of debility and quality of life in humans. The development of new therapeutic approaches to treat neurodegenerative diseases remains a major focus of research and is an attractive field for the development of new treatments.

TSPAN13: A Key Member of the Transmembrane 4 Superfamily
TSPAN13 is a protein that belongs to the Transmembrane 4 Superfamily. This family of proteins includes various signaling molecules that play important roles in intracellular signaling. TSPAN13 is characterized by its unique structure, which consists of four transmembrane domains and a cytoplasmic tail. Its cytoplasmic tail is composed of a variety of tails, each of which plays a different role in intracellular signaling.

Functions and Interactions:
TSPAN13 is involved in various cellular processes that are essential for the proper functioning of neurons. Its functions include regulating the distribution of intracellular signaling molecules, such as neurotransmitters, and modulating the activity of various signaling pathways.

One of the key functions of TSPAN13 is its role in intracellular signaling. It is involved in the regulation of the activity of various signaling pathways, including the nervous system, the endocrine system, and the immune system. TSPAN13 has been shown to play important roles in the regulation of neurotransmitter release, synaptic plasticity, and the modulation of cellular signaling pathways.

Drug Targets:
TSPAN13 has been identified as a potential drug target in neurodegenerative diseases due to its unique structure and its involvement in various cellular processes. Its potential drug targets include the regulation of neurotransmitter release, synaptic plasticity, and the modulation of cellular signaling pathways.

The regulation of neurotransmitter release is a critical function of TSPAN13. It is involved in the regulation of the release of neurotransmitters, including dopamine, serotonin, and endocannabinoids. TSPAN13 has been shown to play a key role in the regulation of neurotransmitter release by modulating the activity of various signaling pathways.

The modulation of cellular signaling pathways is another function of TSPAN13. It is involved in the regulation of various signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway. TSPAN13 has been shown to play a key role in the regulation of cellular signaling pathways by modulating the activity of various signaling molecules.

Conclusion:
TSPAN13 is a protein that has been identified as a potential drug target in neurodegenerative diseases due to its unique structure and its involvement in various cellular processes. Its functions include regulating the distribution of intracellular signaling molecules and modulating the activity of various signaling pathways. Further research is needed to fully understand the potential drug targets of TSPAN13 and its role in the development of new therapeutic approaches for neurodegenerative diseases.

Protein Name: Tetraspanin 13

More Common Targets

TSPAN14 | TSPAN15 | TSPAN16 | TSPAN17 | TSPAN18 | TSPAN19 | TSPAN2 | TSPAN3 | TSPAN31 | TSPAN32 | TSPAN33 | TSPAN4 | TSPAN5 | TSPAN6 | TSPAN7 | TSPAN8 | TSPAN9 | TSPEAR | TSPEAR-AS1 | TSPEAR-AS2 | TSPO | TSPO2 | TSPOAP1 | TSPOAP1-AS1 | TSPY1 | TSPY2 | TSPY26P | TSPY3 | TSPY4 | TSPYL1 | TSPYL2 | TSPYL4 | TSPYL5 | TSPYL6 | TSR1 | TSR2 | TSR3 | TSSC2 | TSSC4 | TSSK1B | TSSK2 | TSSK3 | TSSK4 | TSSK6 | TST | TSTD1 | TSTD2 | TSTD3 | TTBK1 | TTBK2 | TTC1 | TTC12 | TTC13 | TTC14 | TTC16 | TTC17 | TTC19 | TTC21A | TTC21B | TTC21B-AS1 | TTC22 | TTC23 | TTC23L | TTC24 | TTC26 | TTC27 | TTC28 | TTC28-AS1 | TTC29 | TTC3 | TTC3-AS1 | TTC30A | TTC30B | TTC31 | TTC32 | TTC33 | TTC34 | TTC36 | TTC38 | TTC39A | TTC39A-AS1 | TTC39B | TTC39C | TTC39C-AS1 | TTC3P1 | TTC4 | TTC41P | TTC5 | TTC6 | TTC7A | TTC7B | TTC8 | TTC9 | TTC9-DT | TTC9B | TTC9C | TTF1 | TTF2 | TTI1 | TTI2