Target Name: SLC51A
NCBI ID: G200931
Other Name(s): MGC39807 | Organic solute transporter, alpha subunit | Organic solute transporter alpha | OSTA_HUMAN | OSTalpha | Organic solute transporter subunit alpha | solute carrier family 51 subunit alpha | OST-alpha | organic solute transporter alpha | Organic solute transporter subunit alpha (isoform X1) | SLC51A variant X1 | OTTHUMP00000208487 | solute carrier family 51 alpha subunit | OSTA | PFIC6 | organic solute transporter, alpha subunit | Solute carrier family 51, alpha subunit, transcript variant X1 | Solute carrier family 51 subunit alpha

SLC51A: A Protein Involved in Intracellular Signaling and Cellular Processes

SLC51A (MGC39807) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the selective matrix protein (SMP) family, which is a family of transmembrane proteins that play a variety of roles in cellular signaling and structure.

One of the functions of SLC51A is its role in intracellular signaling. It is a key protein in the regulation of the exchange of calcium ions (Ca2+) in and out of cells, which is important for a variety of physiological processes, including muscle contractions, nerve signaling, and blood clotting.

SLC51A is also involved in the regulation of the level of phosphate ions (PO42-) in cells, which is important for maintaining the stability of cellular structures and for signaling the presence of certain molecules in the cell.

In addition to its role in intracellular signaling, SLC51A is also involved in the regulation of cellular processes that are outside of the cell membrane, such as the production and degradation of proteins. It is a key protein in the regulation of protein synthesis, which is the process by which cells produce the proteins that they need to perform their functions.

SLC51A is also involved in the regulation of the transport of molecules across the cell membrane. It is a member of the TRPV4 receptor, which is a family of ion channels that are involved in the regulation of pain, inflammation, and body temperature.

SLC51A is a protein that is expressed in a wide range of tissues and cells of the body. It is involved in a variety of cellular processes that are important for maintaining the structure and function of cells. As a drug target or biomarker, SLC51A may be targeted by researchers to study the effects of drugs on cellular signaling and structure.

Protein Name: Solute Carrier Family 51 Subunit Alpha

Functions: Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood (PubMed:16317684). Efficiently transports the major species of bile acids (taurocholate) (PubMed:16317684). Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (By similarity). Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols (PubMed:16317684). Able to transport eicosanoids such as prostaglandin E2 (By similarity)

More Common Targets

SLC51B | SLC52A1 | SLC52A2 | SLC52A3 | SLC5A1 | SLC5A10 | SLC5A11 | SLC5A12 | SLC5A2 | SLC5A3 | SLC5A4 | SLC5A4-AS1 | SLC5A5 | SLC5A6 | SLC5A7 | SLC5A8 | SLC5A9 | SLC66A1 | SLC66A1L | SLC66A2 | SLC66A3 | SLC6A1 | SLC6A1-AS1 | SLC6A10P | SLC6A10PB | SLC6A11 | SLC6A12 | SLC6A13 | SLC6A14 | SLC6A15 | SLC6A16 | SLC6A17 | SLC6A18 | SLC6A19 | SLC6A2 | SLC6A20 | SLC6A3 | SLC6A4 | SLC6A5 | SLC6A6 | SLC6A7 | SLC6A8 | SLC6A9 | SLC7A1 | SLC7A10 | SLC7A11 | SLC7A11-AS1 | SLC7A13 | SLC7A14 | SLC7A2 | SLC7A3 | SLC7A4 | SLC7A5 | SLC7A5P1 | SLC7A5P2 | SLC7A6 | SLC7A6OS | SLC7A7 | SLC7A8 | SLC7A9 | SLC8A1 | SLC8A1-AS1 | SLC8A2 | SLC8A3 | SLC8B1 | SLC9A1 | SLC9A2 | SLC9A3 | SLC9A3-AS1 | SLC9A4 | SLC9A5 | SLC9A6 | SLC9A7 | SLC9A7P1 | SLC9A8 | SLC9A9 | SLC9A9-AS1 | SLC9B1 | SLC9B1P2 | SLC9B2 | SLC9C1 | SLC9C2 | SLCO1A2 | SLCO1B1 | SLCO1B3 | SLCO1B7 | SLCO1C1 | SLCO2A1 | SLCO2B1 | SLCO3A1 | SLCO4A1 | SLCO4A1-AS1 | SLCO4C1 | SLCO5A1 | SLCO6A1 | SLED1 | SLF1 | SLF2 | SLFN11 | SLFN12