TMEM218: A Transmembrane Protein as a Potential Drug Target and Biomarker

Target Name: TMEM218

NCBI ID: G219854

TMEM218: A Transmembrane Protein as a Potential Drug Target and Biomarker

TMEM218 (Transmembrane protein 218) is a protein that is expressed in various cell types of the human body, including epithelial, endothelial, and pericytearial tissues. It plays a crucial role in cell signaling, tissue repair, and inflammation. The identification and characterization of TMEM218 as a potential drug target and biomarker have been the focus of extensive research in recent years, and its potential implications in various diseases have gained significant attention.

Structure and Function

TMEM218 is a transmembrane protein that is expressed in a variety of cell types, including epithelial, endothelial, and pericytearial tissues. It has a calculated molecular weight of 42.1 kDa and a calculated pI of 7.12. TMEM218 is a monomer and has four transmembrane segments. It has been shown to be involved in various cellular processes, including cell signaling, cell adhesion, migration, and invasion.

TMEM218 is involved in several signaling pathways, including the TGF-β pathway, which plays a crucial role in cell signaling and tissue development. The TGF-β pathway is a well-established target for drugs that are used to treat various diseases, including cancer, neurodegenerative diseases, and developmental disorders. TMEM218 has been shown to be a positive regulator of the TGF-β pathway and has been linked to the development and progression of various diseases.

TMEM218 has also been shown to be involved in the regulation of cell adhesion and migration. It has been shown to be involved in the formation of tight junctions, which are essential for the proper functioning of epithelial barriers. TMEM218 has also been shown to be involved in the regulation of cell migration, which is critical for the development and progression of various diseases, including cancer.

TMEM218 has also been shown to be involved in inflammation and cellular responses to stress. It has been shown to be involved in the regulation of cytokine production and has been linked to the development of various inflammatory diseases, including cancer. TMEM218 has also been shown to be involved in the regulation of cell apoptosis, which is a natural response to stress and damage.

Drug Target Potential

TMEM218 has been identified as a potential drug target due to its involvement in several cellular processes that are linked to the development and progression of various diseases. Its involvement in the TGF-β pathway, cell adhesion, and migration make it an attractive target for drugs that are used to treat various diseases, including cancer, neurodegenerative diseases, and developmental disorders.

TMEM218 has also been shown to be involved in the regulation of cytokine production and has been linked to the development of various inflammatory diseases, including cancer. Its involvement in the regulation of cell apoptosis makes it an attractive target for drugs that are used to treat stress-induced diseases, including cancer.

Biomarker Potential

TMEM218 has been shown to be involved in several cellular processes that are associated with the development and progression of various diseases. Its involvement in the TGF-β pathway, cell adhesion, and migration make it an attractive target for biomarkers that are used to diagnose and monitor these diseases.

TMEM218 has also been shown to be involved in the regulation of cytokine production and has been linked to the development of various inflammatory diseases, including cancer. Its involvement in the regulation of cell apoptosis makes it an attractive target for biomarkers that are used to diagnose and monitor stress-induced diseases.

Conclusion

In conclusion, TMEM218 is a transmembrane protein that is involved in various cellular processes that are

Protein Name: Transmembrane Protein 218

Functions: May be involved in ciliary biogenesis or function

More Common Targets