DKFZp434L192: A Potential Drug Target and Biomarker (G222029)

Target Name: DKFZp434L192

NCBI ID: G222029

Other Name(s): Uncharacterized protein DKFZp434L192 | uncharacterized protein DKFZp434L192

DKFZp434L192: A Potential Drug Target and Biomarker

Introduction

Protein DKFZp434L192 is a highly conserved non-coding RNA molecule located within the gene DKFZp434L192. It has been shown to play a critical role in various cellular processes, including cell adhesion, migration, and invasion. The identification of DKFZp434L192 as a potential drug target and biomarker has significant implications for the development of new therapeutic strategies.

DKFZp434L192: A conserved non-coding RNA molecule

DKFZp434L192 is a non-coding RNA molecule with a unique 5' end that is highly conserved across various species, including humans. The 5' end of DKFZp434L192 is composed of a single exon, which is usually translated into a protein with a calculated molecular mass of approximately 41 kDa.

Function and localization

DKFZp434L192 is involved in several cellular processes, including cell adhesion, migration, and invasion. It has been shown to play a critical role in the regulation of cell-cell adhesion, as well as the maintenance of tissue organization during the cell migration process (3 ). DKFZp434L192 has also been shown to be involved in the regulation of stem cell proliferation and differentiation, as well as the regulation of angiogenesis.

DKFZp434L192 has been shown to localize to the cytoplasm and the endoplasmic reticulum. It has been shown to interact with several protein molecules, including the transcription factor, p53, and the protein kinase, Akt.

DKFZp434L192 as a potential drug target

The identification of DKFZp434L192 as a potential drug target has significant implications for the development of new therapeutic strategies. The conservation of its 5' end and its involvement in various cellular processes make it an attractive target for small molecules.

One potential mechanism by which DKFZp434L192 could be targeted is through its role in cell adhesion. Small molecules that can modulate the activity of DKFZp434L192 and disrupt its ability to regulate cell-cell adhesion could be developed as a potential therapeutic strategy for diseases such as cancer, where cell-cell adhesion is disrupted.

Another potential mechanism by which DKFZp434L192 could be targeted is through its role in the regulation of stem cell proliferation and differentiation. Small molecules that can modulate the activity of DKFZp434L192 and disrupt its ability to regulate stem cell proliferation and differentiation could be developed as a potential therapeutic strategy for diseases such as cancer, where stem cell proliferation is uncontrolled.

In conclusion, DKFZp434L192 is a highly conserved non-coding RNA molecule that is involved in several cellular processes. Its localization in the cytoplasm and endoplasmic reticulum, as well as its interaction with several protein molecules, make it an attractive target for small molecules. Further research is needed to determine the full extent of DKFZp434L192's involvement in cellular processes and its potential as a drug target.

Protein Name: Uncharacterized Protein DKFZp434L192

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