DLGAP5: A Unique Protein with Potential Drug Targeting and Biomarker Properties

Target Name: DLGAP5

NCBI ID: G9787

DLGAP5: A Unique Protein with Potential Drug Targeting and Biomarker Properties

DLGAP5 (KiAA0008) is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and muscle. It is a member of the KIAA class of proteins, which are known as the K-type ATP-binding proteins. This protein is of particular interest as a potential drug target or biomarker due to its unique structure and the diseases it is associated with.

DLGAP5 is characterized by its ability to bind to ATP and its role in various cellular processes. It plays a significant role in the regulation of cell adhesion, as well as in the development and maintenance of tissues. It is also involved in the regulation of muscle contraction and in the progression of certain diseases, such as cancer.

One of the key features of DLGAP5 is its ability to interact with multiple protein partners, including other KIAA proteins and non-KIAA proteins. This makes it a potential target for drugs that can modulate its activity and activity levels. Additionally, its expression is often altered in various diseases, including cancer, which suggests that it may be a valuable biomarker for this disease.

DLGAP5 has also been shown to play a role in the regulation of cellular signaling pathways. It is a component of several signaling pathways that are involved in the regulation of cell growth, differentiation, and survival. Its involvement in these processes makes it a potential target for drugs that can modulate the activity of these signaling pathways.

In addition to its potential drug-target and biomarker properties, DLGAP5 is also of interest due to its unique structure. It is a member of the KIAA class of proteins, which are characterized by their ability to bind to ATP and their lack of a conserved active site. This makes them unique in their ability to regulate ATP binding and metabolism.

The structure of DLGAP5 is also of particular interest as it is involved in the regulation of the actin cytoskeleton. It is a key component of the cytoskeleton and plays a role in the regulation of cell movement and the maintenance of cell structure. The disruption of DLGAP5 function has been observed to lead to changes in the actin cytoskeleton, which can have implications for the regulation of cellular processes.

In conclusion, DLGAP5 is a protein that is of potential interest as a drug target or biomarker due to its unique structure and its involvement in various cellular processes. Its ability to interact with multiple protein partners and its involvement in the regulation of cellular signaling pathways and actin cytoskeleton make it a promising target for drugs that can modulate its activity. Further research is needed to fully understand its role in the regulation of cellular processes and its potential as a drug or biomarker.

Protein Name: DLG Associated Protein 5

Functions: Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells

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