Target Name: TBC1D9B
NCBI ID: G23061
Other Name(s): TBC1 domain family member 9B (isoform a) | TBC1 domain family, member 9B (with GRAM domain) | GRAMD9B | KIAA0676 | TBC9B_HUMAN | TBC1D9B variant 1 | TBC1 domain family member 9B, transcript variant 1 | TBC1 domain family member 9B

TBC1D9B: A Potential Drug Target and Biomarker

TBC1D9B (TBC1 domain family member 9B) is a protein that has been identified as a potential drug target and biomarker. It is a key regulator of the TBC1 gene family, which is involved in various cellular processes, including cell adhesion, migration, and invasion. The TBC1D9B protein has been shown to play a crucial role in these processes, and its dysfunction has been linked to various diseases, including cancer.

The TBC1D9B Protein

TBC1D9B is a 21-kDa protein that is expressed in various tissues, including brain, pancreas, and gastrointestinal tract. It is a member of the TBC1 gene family, which consists of six genes (TBC1A, TBC1B, TBC1C, TBC1D, TBC1E, and TBC1F) that are involved in the regulation of cell adhesion, migration, and invasion. The TBC1D9B protein is a key regulator of the TBC1 gene family, and its dysfunction has been linked to the development and progression of various diseases.

Drug Target Potential

TBC1D9B has been shown to be a potential drug target due to its involvement in various cellular processes that are crucial for the development and progression of diseases. For example, TBC1D9B has been shown to play a role in the regulation of cell adhesion, which is a critical process for the development of cancer. In addition, TBC1D9B has been shown to be involved in the regulation of cell migration and invasion, which are critical processes for the development of many diseases, including cancer.

Biomarker Potential

TBC1D9B has also been identified as a potential biomarker for various diseases. For example, TBC1D9B has been shown to be involved in the regulation of cancer cell invasion and metastasis. In addition, TBC1D9B has been shown to be involved in the regulation of insulin sensitivity, which is a critical factor in the development of type 2 diabetes.

Expression and Function

TBC1D9B is highly expressed in various tissues and has been shown to play a critical role in the regulation of cellular processes. For example, TBC1D9B has been shown to be involved in the regulation of cell adhesion, as well as the regulation of cell migration and invasion. In addition, TBC1D9B has been shown to play a role in the regulation of insulin sensitivity, which is a critical factor in the development of type 2 diabetes.

Conclusion

TBC1D9B is a protein that has been identified as a potential drug target and biomarker. Its dysfunction has been linked to various diseases, including cancer and type 2 diabetes. Further research is needed to fully understand the role of TBC1D9B in these diseases and to develop effective treatments.

Protein Name: TBC1 Domain Family Member 9B

Functions: May act as a GTPase-activating protein for Rab family protein(s)

More Common Targets

TBCA | TBCB | TBCC | TBCCD1 | TBCD | TBCE | TBCEL | TBCK | TBILA | TBK1 | TBKBP1 | TBL1X | TBL1XR1 | TBL1Y | TBL2 | TBL3 | TBP | TBPL1 | TBPL2 | TBR1 | TBRG1 | TBRG4 | TBX1 | TBX10 | TBX15 | TBX18 | TBX18-AS1 | TBX19 | TBX2 | TBX20 | TBX21 | TBX22 | TBX3 | TBX4 | TBX5 | TBX5-AS1 | TBX6 | TBXA2R | TBXAS1 | TBXT | TC2N | TCAF1 | TCAF1P1 | TCAF2 | TCAIM | TCAM1P | TCAP | TCEA1 | TCEA1P2 | TCEA2 | TCEA3 | TCEAL1 | TCEAL2 | TCEAL3 | TCEAL4 | TCEAL5 | TCEAL6 | TCEAL7 | TCEAL8 | TCEAL9 | TCEANC | TCEANC2 | TCERG1 | TCERG1L | TCF12 | TCF12-DT | TCF15 | TCF19 | TCF20 | TCF21 | TCF23 | TCF24 | TCF25 | TCF3 | TCF4 | TCF7 | TCF7L1 | TCF7L2 | TCFL5 | TCHH | TCHHL1 | TCHP | TCIM | TCIRG1 | TCL1A | TCL1B | TCL6 | TCN1 | TCN2 | TCOF1 | TCP1 | TCP10L | TCP10L2 | TCP10L3 | TCP11 | TCP11L1 | TCP11L2 | TCP11X2 | TCTA | TCTE1