TBX4: A Potential Drug Target for Neurodegenerative Diseases (G9496)
TBX4: A Potential Drug Target for Neurodegenerative Diseases
TBX4 (T-box protein 4) is a protein that is expressed in a variety of tissues throughout the body, including the brain, heart, kidneys, and liver. It is a member of the T-box gene family, which encodes a family of proteins that play a role in cell-cell signaling.
The T-box genes were identified in the late 1990s as potential drug targets because they are involved in the regulation of cell growth, differentiation, and survival. The T-box proteins are thought to interact with various signaling pathways, including the TGF-β pathway, which plays a central role in regulating cell growth and differentiation.
TBX4 is a 21-kDa protein that is expressed in the brain, heart, kidneys, and liver. It is highly conserved, with a calculated pI of 5.5. TBX4 is a protein that is involved in the regulation of cell adhesion, migration, and survival. It is also involved in the regulation of the cytoskeleton and in the regulation of cellular signaling pathways, including the TGF-β pathway.
TBX4 is a protein that has been identified as a potential drug target in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Because it is involved in the regulation of cell signaling pathways, TBX4 may be a useful biomarker for the diagnosis and treatment of these diseases.
In addition to its potential as a drug target, TBX4 is also a protein that is involved in the regulation of cellular processes that are important for the maintenance of brain health and function. It is thought to be involved in the regulation of neurotransmitter release from neurons, which is important for the functioning of the brain.
TBX4 is also involved in the regulation of the formation and maintenance of the blood-brain barrier, which is a barrier that separates the brain from the surrounding blood vessels and is thought to play an important role in the regulation of brain health and function.
In conclusion, TBX4 is a protein that is involved in the regulation of a variety of cellular processes that are important for the maintenance of brain health and function. As a potential drug target, TBX4 may be a useful target for the diagnosis and treatment of a variety of neurodegenerative diseases. Further research is needed to fully understand the role of TBX4 in these processes and to develop effective treatments.
Protein Name: T-box Transcription Factor 4
Functions: Transcriptional regulator that has an essential role in the organogenesis of lungs, pelvis, and hindlimbs
More Common Targets
TBX5 | TBX5-AS1 | TBX6 | TBXA2R | TBXAS1 | TBXT | TC2N | TCAF1 | TCAF1P1 | TCAF2 | TCAIM | TCAM1P | TCAP | TCEA1 | TCEA1P2 | TCEA2 | TCEA3 | TCEAL1 | TCEAL2 | TCEAL3 | TCEAL4 | TCEAL5 | TCEAL6 | TCEAL7 | TCEAL8 | TCEAL9 | TCEANC | TCEANC2 | TCERG1 | TCERG1L | TCF12 | TCF12-DT | TCF15 | TCF19 | TCF20 | TCF21 | TCF23 | TCF24 | TCF25 | TCF3 | TCF4 | TCF7 | TCF7L1 | TCF7L2 | TCFL5 | TCHH | TCHHL1 | TCHP | TCIM | TCIRG1 | TCL1A | TCL1B | TCL6 | TCN1 | TCN2 | TCOF1 | TCP1 | TCP10L | TCP10L2 | TCP10L3 | TCP11 | TCP11L1 | TCP11L2 | TCP11X2 | TCTA | TCTE1 | TCTN1 | TCTN2 | TCTN3 | TDG | TDGF1 | TDGF1P3 | TDGP1 | TDH | TDH-AS1 | TDO2 | TDP1 | TDP2 | TDRD1 | TDRD10 | TDRD12 | TDRD15 | TDRD3 | TDRD5 | TDRD6 | TDRD7 | TDRD9 | TDRG1 | TDRKH | TDRKH-AS1 | TDRP | TEAD1 | TEAD2 | TEAD3 | TEAD4 | TEC | TECPR1 | TECPR2 | TECR | TECRL