TDH-AS1: A Potential Drug Target and Biomarker (G100129129)

Target Name: TDH-AS1

NCBI ID: G100129129

Other Name(s): TDH antisense RNA 1

TDH-AS1: A Potential Drug Target and Biomarker

TDH-AS1 (Tumor suppressor gene-encoded attractor) is a protein that is expressed in various tissues of the human body, including the brain, pancreas, and gastrointestinal tract. It is a potential drug target and biomarker for various diseases, including cancer.

TDH-AS1 is a transmembrane protein that is expressed in the endoplasmic reticulum (ER) and cytoplasm. It has a molecular weight of approximately 41 kDa and a pre-fusion protein of 25 kDa. TDH-AS1 is highly conserved sequence-wise and has been shown to have similar structures to other tumor suppressor genes, such as p53 and Rb.

TDH-AS1 functions as a tumor suppressor gene-encoded attractor (TSA). It can interact with and activate various transcription factors, including p53, to promote the expression of target genes that are involved in cell growth, apoptosis, and other cellular processes. TDH-AS1 has been shown to play a role in the regulation of cell cycle progression, apoptosis, and angiogenesis.

TDH-AS1 has been shown to be involved in various diseases, including cancer. For example, it has been shown to be involved in the regulation of cancer cell growth and apoptosis. TDH-AS1 has also been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed in the body. This is important for diseases such as cancer, where the growth of new blood vessels can contribute to tumor growth.

TDH-AS1 may also be a potential biomarker for certain diseases. For example, it has been shown to be involved in the regulation of cell apoptosis, which is the process by which cells die naturally. This may be important for diseases such as neurodegenerative disorders, where the regulation of cell apoptosis is disrupted.

TDH-AS1 may also be a potential drug target for diseases that are caused by the disruption of normal cellular processes, such as cancer. For example, TDH-AS1 has been shown to be involved in the regulation of cell cycle progression, which is the process by which cells grow and divide. This may be important for diseases such as cancer, where the regulation of cell cycle progression is disrupted.

TDH-AS1 has been shown to be involved in the regulation of various cellular processes, including cell growth, apoptosis, and angiogenesis. It may also be a potential drug target and biomarker for various diseases. Further research is needed to fully understand the role of TDH-AS1 in these processes and to develop effective treatments for diseases that are caused by its disruption.

Protein Name: TDH Antisense RNA 1

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