INTS4P1: Key Component of TGF-β Pathway (G285905)

Target Name: INTS4P1

NCBI ID: G285905

Other Name(s): Integrator complex subunit 4-like 1 | integrator complex subunit 4 pseudogene 1 | INTS4L1

INTS4P1: Key Component of TGF-β Pathway

INTS4P1, also known as Integrator complex subunit 4-like 1, is a protein that is expressed in various tissues and cells throughout the body. It is a key component of the intracellular signaling pathway known as the TGF-β pathway, which plays a crucial role in cell growth, differentiation, and survival.

The TGF-β pathway is a complex signaling pathway that is involved in the regulation of cellular processes such as cell growth, angiogenesis, and immune responses. The pathway is composed of several transcription factors, including TGF-β1, which is a potent regulator growth factors, and its downstream targets, such as INGS1, INSR2, and KLF1.

INTS4P1 is a 22-kDa protein that is expressed in various tissues and cells, including muscle, heart, liver, and brain. It is a key component of the TGF-β pathway, as it is able to activate the signaling pathway in response to TGF-β1. INTS4P1 functions as a negative regulator of the TGF-β pathway, by binding to the TGF-β1 receptor and preventing it from activating the pathway.

The TGF-β pathway is involved in the regulation of many cellular processes, including cell growth, angiogenesis, and stem cell maintenance. It is also involved in the regulation of immune responses, as well as in the regulation of cellular signaling pathways that are involved in cell survival and reproduction.

INTS4P1 is a potential drug target, as it is a key component of the TGF-β pathway, which is a promising target for the development of new pharmaceuticals for a variety of diseases, including cancer, cardiovascular disease, and autoimmune disorders.

There is also some evidence to suggest that INTS4P1 may be a biomarker for certain diseases, such as cancer. INTS4P1 has been shown to be overexpressed in a variety of cancer tissues, and it has been suggested that it may be a useful biomarker for the diagnosis and prognosis of certain types of cancer.

In conclusion, INTS4P1 is a key component of the TGF-β pathway, which is a complex signaling pathway that is involved in the regulation of many cellular processes. It is a potential drug target and biomarker for a variety of diseases, including cancer. Further research is needed to fully understand the role of INTS4P1 in cellular signaling and its potential as a therapeutic target.

Protein Name: Integrator Complex Subunit 4 Pseudogene 1

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