Target Name: ISG20
NCBI ID: G3669
Other Name(s): ISG20_HUMAN | Promyelocytic leukemia nuclear body-associated protein ISG20 | ISG20 variant 1 | estrogen-regulated transcript 45 protein | interferon stimulated exonuclease gene 20kDa | Interferon-stimulated gene 20 kDa protein (isoform a) | CD25 | Interferon stimulated exonuclease gene 20, transcript variant 1 | promyelocytic leukemia nuclear body-associated protein ISG20 | Interferon-stimulated gene 20 kDa protein | HEM45 | interferon stimulated exonuclease gene 20 | Estrogen-regulated transcript 45 protein

ISG20 Gene as Drug Target for Various Diseases

The ISG20 (ISG20_HUMAN) gene is a non-coding RNA molecule that has been identified as a potential drug target in the field of human genetics. ISG20 is a key regulator of stem cell proliferation and has been shown to play a role in the development and maintenance of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The ISG20 gene has been identified as a potential drug target due to its involvement in several cellular processes that are associated with the development and progression of various diseases. For example, ISG20 has been shown to promote the growth and survival of cancer cells, and has been linked to the development of various types of cancer.

In addition to its role in cancer, ISG20 has also been linked to the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. ISG20 has been shown to promote the development of neurodegenerate brain cells and has been linked to the misfolding of certain proteins that are involved in neurodegeneration.

Furthermore, ISG20 has also been associated with the development of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. ISG20 has been shown to regulate the immune system and has been linked to the development of autoimmune diseases.

Drugs that target ISG20 have the potential to treat a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. ISG20 has also been shown to be a promising biomarker for several diseases, including cancer and neurodegenerative diseases.

The ISG20 gene has also been the subject of extensive research in the field of stem cell biology. ISG20 has been shown to play a key role in the regulation of stem cell proliferation and has been linked to the development and maintenance of stem cells.

In conclusion, ISG20 is a gene that has the potential to be a drug target for a wide range of diseases. ISG20 has been shown to promote the growth and survival of cancer cells, and has been linked to the development of various types of cancer. ISG20 has also been linked to the development of neurodegenerative diseases and autoimmune disorders. Furthermore, ISG20 has been shown to play a key role in the regulation of stem cell proliferation and has been linked to the development and maintenance of stem cells. Further research is needed to fully understand the role of ISG20 in disease and to develop effective treatments.

Protein Name: Interferon Stimulated Exonuclease Gene 20

Functions: Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis

More Common Targets

ISG20L2 | ISL1 | ISL1-DT | ISL2 | ISLR | ISLR2 | ISM1 | ISM2 | ISOC1 | ISOC2 | Isocitrate dehydrogenase 3 (NAD+) | Isocitrate dehydrogenases | Isoleucyl-tRNA synthetase | IST1 | ISWI Chromatin Remodeling Complex | ISX | ISY1 | ISY1-RAB43 | ISYNA1 | ITCH | ITFG1 | ITFG2 | ITFG2-AS1 | ITGA1 | ITGA10 | ITGA11 | ITGA2 | ITGA2B | ITGA3 | ITGA4 | ITGA5 | ITGA6 | ITGA6-AS1 | ITGA7 | ITGA8 | ITGA9 | ITGAD | ITGAE | ITGAL | ITGAM | ITGAV | ITGAX | ITGB1 | ITGB1BP1 | ITGB1BP2 | ITGB1P1 | ITGB2 | ITGB2-AS1 | ITGB3 | ITGB3BP | ITGB4 | ITGB5 | ITGB6 | ITGB7 | ITGB8 | ITGBL1 | ITIH1 | ITIH2 | ITIH3 | ITIH4 | ITIH5 | ITIH6 | ITK | ITLN1 | ITLN2 | ITM2A | ITM2B | ITM2C | ITPA | ITPK1 | ITPK1-AS1 | ITPKA | ITPKB | ITPKB-IT1 | ITPKC | ITPR1 | ITPR1-DT | ITPR2 | ITPR3 | ITPRID1 | ITPRID2 | ITPRIP | ITPRIPL1 | ITPRIPL2 | ITSN1 | ITSN2 | IVD | IVL | IVNS1ABP | IWS1 | IYD | IZUMO1 | IZUMO1R | IZUMO2 | IZUMO4 | JADE1 | JADE2 | JADE3 | JAG1 | JAG2