Target Name: ITGA10
NCBI ID: G8515
Other Name(s): Integrin subunit alpha 10, transcript variant 1 | PRO827 | Integrin subunit alpha 10, transcript variant 2 | Integrin subunit alpha 10, transcript variant 3 | ITGA10 variant 3 | Integrin alpha-10 | integrin subunit alpha 10 | ITA10_HUMAN | ITGA10 variant 2 | Integrin alpha-10 (isoform 3) | Integrin alpha-10 (isoform 2) | Integrin alpha-10 (isoform 1) | ITGA10 variant 1 | integrin alpha-10-like | Integrin alpha 10

Unlocking the Potential of ITGA10 as a Drug Target: A Comprehensive Analysis

Abstract:

ITGA10, a subunit of integrin alpha-10, has been identified as a potential drug target and biomarker for various diseases. This article will summarize the current research on ITGA10, its potential drug targets, and its potential as a biomarker.

Introduction:

Integrin alpha-10 (ITGA10) is a protein that plays a critical role in cell-cell adhesion, migration, and invasion. It is a member of the integrin alpha family, which consists of six subunits that form the core of integrin molecules. ITGA10 is expressed in various tissues and is involved in many physiological processes, including embryonic development, tissue repair, and cancer progression.

Recent studies have identified ITGA10 as a potential drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its potential as a drug target is based on its unique structure, its expression in various tissues, and its involvement in multiple cellular processes.

Drug Targets:

1. inhibition of ITGA10-mediated cell-cell adhesion:

Many studies have shown that ITGA10 plays a critical role in cell-cell adhesion. ITGA10 interacts with various adhesion molecules, including cadherins, integrins, and heparins. Therefore, inhibitors that target ITGA10-mediated cell-cell adhesion could be effective in treating various diseases, including cancer.

2. targeting ITGA10 in neurodegenerative diseases:

Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, are characterized by the progressive loss of brain cells. It is well known that these diseases are associated with the accumulation of ITGA10 in the brain. Therefore, targeting ITGA10 with drugs that can remove it from the brain could be an effective strategy for treating neurodegenerative diseases.

3. inhibition of ITGA10-mediated cancer progression:

ITGA10 has been shown to be involved in cancer cell proliferation and migration. Therefore, inhibitors that target ITGA10-mediated cancer cell processes could be effective in treating various types of cancer.

Biomarkers:

1. ITGA10 as a potential biomarker for cancer:

ITGA10 has been shown to be involved in cancer cell proliferation and migration. Therefore, its levels can be used as a biomarker for cancer. Studies have shown that ITGA10 levels are higher in various types of cancer, including breast, lung, and ovarian cancer. Therefore, ITGA10 could be an attractive biomarker for cancer diagnosis and treatment.

2. ITGA10 as a potential biomarker for neurodegenerative diseases:

ITGA10 has been shown to be involved in the development and progression of neurodegenerative diseases. Therefore, its levels can be used as a biomarker for neurodegenerative diseases. Studies have shown that ITGA10 levels are higher in various neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Therefore, ITGA10 could be an attractive biomarker for neurodegenerative diseases.

Conclusion:

ITGA10 is a protein that plays a critical role in cell-cell adhesion, migration, and invasion. Its unique structure and expression in various tissues make it an attractive target for drug development. recent studies have shown that ITGA10 is involved in multiple cellular processes and has been identified as a potential drug target for various diseases, including cancer and neurodegenerative diseases. Therefore, further research is needed to fully understand ITGA10's role in

Protein Name: Integrin Subunit Alpha 10

Functions: Integrin alpha-10/beta-1 is a receptor for collagen

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ITGA11 | ITGA2 | ITGA2B | ITGA3 | ITGA4 | ITGA5 | ITGA6 | ITGA6-AS1 | ITGA7 | ITGA8 | ITGA9 | ITGAD | ITGAE | ITGAL | ITGAM | ITGAV | ITGAX | ITGB1 | ITGB1BP1 | ITGB1BP2 | ITGB1P1 | ITGB2 | ITGB2-AS1 | ITGB3 | ITGB3BP | ITGB4 | ITGB5 | ITGB6 | ITGB7 | ITGB8 | ITGBL1 | ITIH1 | ITIH2 | ITIH3 | ITIH4 | ITIH5 | ITIH6 | ITK | ITLN1 | ITLN2 | ITM2A | ITM2B | ITM2C | ITPA | ITPK1 | ITPK1-AS1 | ITPKA | ITPKB | ITPKB-IT1 | ITPKC | ITPR1 | ITPR1-DT | ITPR2 | ITPR3 | ITPRID1 | ITPRID2 | ITPRIP | ITPRIPL1 | ITPRIPL2 | ITSN1 | ITSN2 | IVD | IVL | IVNS1ABP | IWS1 | IYD | IZUMO1 | IZUMO1R | IZUMO2 | IZUMO4 | JADE1 | JADE2 | JADE3 | JAG1 | JAG2 | JAGN1 | JAK1 | JAK2 | JAK3 | JAKMIP1 | JAKMIP1-DT | JAKMIP2 | JAKMIP2-AS1 | JAKMIP3 | JAM2 | JAM3 | JAML | Janus Kinase | JARID2 | JAZF1 | JAZF1-AS1 | JCAD | JDP2 | JHY | JKAMP | JMJD1C | JMJD1C-AS1 | JMJD4 | JMJD6 | JMJD7