Target Name: JHY
NCBI ID: G79864
Other Name(s): Junctional cadherin complex regulator, transcript variant 1 | juvenile hydrocephalus | JHY variant 1 | C11orf63 | Uncharacterized protein C11orf63 | JHY_HUMAN | junctional cadherin complex regulator | Jhy protein homolog (isoform 1) | Jhy protein homolog | uncharacterized protein C11orf63

JHY: Key Regulator of Cell-Cell Adhesion and Potential Drug Target Or Biomarker

JHY (Junctional cadherin complex regulator, transcript variant 1) is a protein that plays a crucial role in cell-cell adhesion and signaling. It is a member of the cadherin family, which is known for its role in cell-cell adhesion and its involvement in various diseases, including cancer. JHY is expressed in various tissues and cells throughout the body and is involved in the regulation of cell-cell adhesion, as well as in the development and progression of various diseases.

JHY is a transcript variant of the cadherin gene, which is responsible for the production of the cadherin protein. The cadherin protein is a transmembrane protein that is involved in cell-cell adhesion and signaling. It is composed of four transmembrane domains: an extracellular domain, a transmembrane domain, an intracellular domain, and an N-terminus. The extracellular domain is involved in cell adhesion, while the transmembrane domains are involved in the regulation of cell-cell adhesion and the intracellular domain is involved in the regulation of cell signaling.

JHY is a key regulator of cell-cell adhesion and has been involved in the development and progression of various diseases. For example, JHY is involved in the regulation of cancer cell-cell adhesion and has been shown to be involved in the development of various types of cancer, including breast, ovarian, and prostate cancer.

In addition to its role in cancer, JHY is also involved in the regulation of normal cell-cell adhesion and has been shown to be involved in the development and progression of various diseases, including neurodegenerative diseases. For example, JHY has been shown to be involved in the development of Alzheimer's disease and has been shown to play a role in the regulation of neurotransmitter release from neurons.

JHY is also involved in the regulation of stem cell proliferation and has been shown to play a role in the development and maintenance of stem cells. For example, JHY has been shown to be involved in the regulation of the self-renewal ability of stem cells and has been shown to play a role in the development of cancer stem cells.

In conclusion, JHY is a protein that is involved in the regulation of cell-cell adhesion and has been shown to be involved in the development and progression of various diseases. As a result, JHY may be a potential drug target or biomarker for the treatment of these diseases. Further research is needed to fully understand the role of JHY in cell-cell adhesion and its potential as a drug target or biomarker.

Protein Name: Junctional Cadherin Complex Regulator

Functions: Required for the normal development of cilia in brain ependymal cells lining the ventricular surfaces

More Common Targets

JKAMP | JMJD1C | JMJD1C-AS1 | JMJD4 | JMJD6 | JMJD7 | JMJD7-PLA2G4B | JMJD8 | JMY | JOSD1 | JOSD2 | JPH1 | JPH2 | JPH3 | JPH4 | JPT1 | JPT2 | JPX | JRK | JRKL | JSRP1 | JTB | JUN | JUNB | JUND | JUP | K(ATP) Channel | KAAG1 | Kainate Receptor (GluR) | Kallikrein | KALRN | KANK1 | KANK2 | KANK3 | KANK4 | KANSL1 | KANSL1-AS1 | KANSL1L | KANSL2 | KANSL3 | KANTR | KARS1 | KARS1P1 | KARS1P2 | KASH5 | KAT14 | KAT2A | KAT2B | KAT5 | KAT6A | KAT6A-AS1 | KAT6B | KAT7 | KAT8 | Katanin Complex | KATNA1 | KATNAL1 | KATNAL2 | KATNB1 | KATNBL1 | KATNBL1P6 | KATNIP | KAZALD1 | KAZN | KAZN-AS1 | KBTBD11 | KBTBD12 | KBTBD13 | KBTBD2 | KBTBD3 | KBTBD4 | KBTBD6 | KBTBD7 | KBTBD8 | KC6 | KCMF1 | KCNA1 | KCNA10 | KCNA2 | KCNA3 | KCNA4 | KCNA5 | KCNA6 | KCNA7 | KCNAB1 | KCNAB2 | KCNAB3 | KCNB1 | KCNB2 | KCNC1 | KCNC2 | KCNC3 | KCNC4 | KCND1 | KCND2 | KCND3 | KCNE1 | KCNE2 | KCNE3 | KCNE4