Unique Kelch Domain-Containing Protein 7B (KBTBD11) (G9920)

Target Name: KBTBD11

NCBI ID: G9920

Unique Kelch Domain-Containing Protein 7B (KBTBD11)

Kelch domain-containing protein 7B (KBTBD11) is a protein that is expressed in various tissues and organs, including the brain, heart, and blood vessels. It is a member of the Kelch domain family of proteins, which are characterized by the presence of a conserved catalytic core and a variable region that includes a unique topology.

KBTBD11 is unique among its kind because of its structure and function. It has a highly conserved catalytic core that is characterized by a characteristic Rossmann-fold, which is a common structural motif that is found in proteins that are involved in catalytic activity. The Rossmann-fold is a specific type of hydrogen bonding that allows the protein to bind to small molecules with high affinity.

In addition to its conserved catalytic core, KBTBD11 also has a variable region that is characterized by a unique topology. The variable region includes a short, linear region that is located at the C-terminus of the protein, as well as a long, linear region that is located between the catalytic core and the C-terminus. The linear regions of KBTBD11 are composed of a series of alternating beta-helices, which are arranged in a specific order.

The unique topology of KBTBD11 is thought to be important for its function. The protein is involved in a variety of cellular processes, including the regulation of signaling pathways, cell adhesion, and inflammation. It is also expressed in various tissues and organs, including the brain, heart, and blood vessels, which suggests that it may be involved in the regulation of important cellular processes that are specific to these tissues.

KBTBD11 is of particular interest as a potential drug target because of its unique structure and function. The conserved catalytic core and variable region suggest that it may be involved in a variety of cellular processes that are important for human health. Additionally, the protein is expressed in various tissues and organs, which suggests that it may be a useful biomarker for the diagnosis and treatment of various diseases.

In conclusion, Kelch domain-containing protein 7B (KBTBD11) is a unique and fascinating protein that is involved in a variety of cellular processes. Its conserved catalytic core and variable region, as well as its expression in various tissues and organs, make it an attractive candidate for further research as a potential drug target or biomarker. Further studies are needed to fully understand the function and potential applications of KBTBD11 in humans.

Protein Name: Kelch Repeat And BTB Domain Containing 11

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