Target Name: JMJD4
NCBI ID: G65094
Other Name(s): jumonji domain-containing protein 4 | OTTHUMP00000035836 | JMJD4 variant 1 | C4 lysyl hydroxylase | 2-oxoglutarate and iron-dependent oxygenase JMJD4 | Jumonji domain containing 4 | lysyl-hydroxylase JMJD4 | MGC129896 | OTTHUMP00000035837 | Lysyl-hydroxylase JMJD4 | JMJD4_HUMAN | Jumonji domain containing 4, transcript variant 1 | jmjC domain-containing protein 4 | 2-oxoglutarate- and Fe(II)-dependent oxygenase | jumonji domain containing 4 | 2-oxoglutarate and iron-dependent oxygenase JMJD4 isoform 1 | Jumonji domain-containing protein 4 | FLJ12517

JMJD4: A Protein Involved in Cell Adhesion and Signaling

JMJD4, also known as jumonji domain-containing protein 4, is a protein that is expressed in various tissues throughout the body. It is a member of the JMJD4 gene family, which is characterized by the presence of a unique domain called the jumonji domain. The jumonji domain is a structural protein that is found in many proteins and is responsible for the protein's unique structure and function.

JMJD4 is a protein that is involved in many different cellular processes in the body. It is a key regulator of cell adhesion, which is the process by which cells stick together to form tissues and organs. JMJD4 is also involved in the regulation of cell signaling , which is the process by which cells communicate with each other to coordinate their activities.

One of the key functions of JMJD4 is its role in cell signaling. It is a negative regulator of the protein kinase PDK4, which is involved in many different cellular processes. By regulating PDK4, JMJD4 helps to maintain the balance between signaling and cell adhesion.

Another important function of JMJD4 is its role in the regulation of cell cycle progression. It is a regulator of the protein cyclin D1, which is involved in the regulation of cell cycle progression.

JMJD4 is also involved in the regulation of many different signaling pathways. It is a negative regulator of the protein tyrosine kinase PDGFR-尾, which is involved in many different cellular processes. It is also a negative regulator of the protein kinase CRK2, which is involved in many different cellular processes.

JMJD4 is a protein that is expressed in various tissues throughout the body, including the brain, heart, and gastrointestinal tract. It is also a good candidate for drug targeting. The jumonji domain is a unique structural protein that is involved in many different cellular processes , making it a potential drug target.

Drug Targeting

JMJD4 is a protein that is involved in many different cellular processes, making it a potential drug target. One of the key targets for JMJD4 is the protein PDK4. PDK4 is a protein that is involved in many different cellular processes, including cell signaling and cell adhesion.

JMJD4 is a negative regulator of PDK4, which means that it helps to reduce the activity of PDK4. By regulating PDK4, JMJD4 helps to maintain the balance between signaling and cell adhesion.

Another potential target for JMJD4 is the protein CRK2. CRK2 is a protein that is involved in many different cellular processes, including cell signaling and cell adhesion. JMJD4 is a negative regulator of CRK2, which means that it helps to reduce the activity of CRK2.

JMJD4 may also be a potential biomarker for certain diseases. The jumonji domain is a unique structural protein that is involved in many different cellular processes. By targeting JMJD4, researchers may be able to develop new treatments for diseases that are caused by the disruption of these processes.

Conclusion

JMJD4 is a protein that is involved in many different cellular processes throughout the body. It is a key regulator of cell adhesion and cell signaling, and it may be a potential drug target or biomarker for certain diseases. Further research is needed to fully understand the functions of JMJD4 and its potential as a drug.

Protein Name: Jumonji Domain Containing 4

Functions: Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1

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JMJD6 | JMJD7 | JMJD7-PLA2G4B | JMJD8 | JMY | JOSD1 | JOSD2 | JPH1 | JPH2 | JPH3 | JPH4 | JPT1 | JPT2 | JPX | JRK | JRKL | JSRP1 | JTB | JUN | JUNB | JUND | JUP | K(ATP) Channel | KAAG1 | Kainate Receptor (GluR) | Kallikrein | KALRN | KANK1 | KANK2 | KANK3 | KANK4 | KANSL1 | KANSL1-AS1 | KANSL1L | KANSL2 | KANSL3 | KANTR | KARS1 | KARS1P1 | KARS1P2 | KASH5 | KAT14 | KAT2A | KAT2B | KAT5 | KAT6A | KAT6A-AS1 | KAT6B | KAT7 | KAT8 | Katanin Complex | KATNA1 | KATNAL1 | KATNAL2 | KATNB1 | KATNBL1 | KATNBL1P6 | KATNIP | KAZALD1 | KAZN | KAZN-AS1 | KBTBD11 | KBTBD12 | KBTBD13 | KBTBD2 | KBTBD3 | KBTBD4 | KBTBD6 | KBTBD7 | KBTBD8 | KC6 | KCMF1 | KCNA1 | KCNA10 | KCNA2 | KCNA3 | KCNA4 | KCNA5 | KCNA6 | KCNA7 | KCNAB1 | KCNAB2 | KCNAB3 | KCNB1 | KCNB2 | KCNC1 | KCNC2 | KCNC3 | KCNC4 | KCND1 | KCND2 | KCND3 | KCNE1 | KCNE2 | KCNE3 | KCNE4 | KCNE5 | KCNF1 | KCNG1 | KCNG2