ITLN2: A Potential Drug Target Or Biomarker (G142683)

Target Name: ITLN2

NCBI ID: G142683

ITLN2: A Potential Drug Target Or Biomarker

The endothelial lectin HL-2 (ITLN2) is a protein that is expressed in the endothelium, which is the lining of the blood vessels. ITLN2 has been shown to play a role in various physiological processes, including blood clotting and vascular barrier function. In addition, ITLN2 has also been shown to be involved in cancer progression and recurrence. As a result, ITLN2 has potential as a drug target or biomarker.

Drug Target Potential

ITLN2 has been shown to be involved in several signaling pathways that are involved in cancer progression and recurrence. One of these signaling pathways is the TGF-β pathway. This pathway is involved in cell growth, differentiation, and angiogenesis, and has been implicated in cancer progression.

Studies have shown that ITLN2 can inhibit the activity of the TGF-β pathway, which suggests that it may be a potential drug target. In addition, ITLN2 has also been shown to interact with several TGF-β pathway proteins, including SMAD4 and TSG101, which further supports its potential as a drug target.

Biomarker Potential

In addition to its potential as a drug target, ITLN2 has also been shown to be a potential biomarker for cancer. Studies have shown that ITLN2 levels are elevated in several types of cancer, including breast, ovarian, and colorectal cancer. This suggests that ITLN2 may be a useful biomarker for these cancers.

In addition, ITLN2 has also been shown to be involved in the development of metastasis. Studies have shown that ITLN2 is involved in the migration and invasion of cancer cells. This suggests that ITLN2 may be a potential biomarker for metastasis.

Pathway Analysis

ITLN2 has been shown to be involved in several signaling pathways, including the TGF-β pathway and the Wnt pathway. The TGF-β pathway is involved in cell growth, differentiation, and angiogenesis, and has been implicated in cancer progression. The Wnt pathway is involved in cell growth and development, and has also been implicated in cancer progression.

Conclusion

In conclusion, ITLN2 is a protein that has been shown to play a role in several physiological processes, including blood clotting, vascular barrier function, cancer progression and recurrence. As a result, ITLN2 has potential as a drug target or biomarker. Further studies are needed to fully understand its role in these processes and its potential as a drug.

Protein Name: Intelectin 2

Functions: May play a role in the defense system against pathogens

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