IGKV3-11: Role in Brain Development and Function (G28914)

Target Name: IGKV3-11

NCBI ID: G28914

Other Name(s): L6 | IGKV311 | immunoglobulin kappa variable 3-11 | Immunoglobulin kappa variable 3-11

IGKV3-11: Role in Brain Development and Function

IGKV3-11 (L6) is a protein that is expressed in various tissues of the body, including the brain. It is a member of the IGK family of proteins, which are involved in intracellular signaling. IGKV3-11 has been shown to play a role in the regulation of cellular processes that are important for brain development and function.

One of the key functions of IGKV3-11 is its role in the development and maintenance of synapses, which are the structures that allow cells to communicate with one another. Synapses are formed during fetal development and are important for the proper functioning of the brain. IGKV3-11 has been shown to be involved in the regulation of the formation and maintenance of synapses, which is important for the development and function of the brain.

Another important function of IGKV3-11 is its role in the regulation of cellular signaling pathways. IGKV3-11 has been shown to be involved in a number of signaling pathways that are important for brain development and function. For example, IGKV3-11 has been shown to be involved in the regulation of the Wnt signaling pathway, which is important for the development and function of the brain.

In addition to its role in the regulation of synapses and cellular signaling pathways, IGKV3-11 is also involved in the regulation of cellular processes that are important for the development and maintenance of tissues. For example, IGKV3-11 has been shown to be involved in the regulation of cell division, which is important for the growth and development of tissues.

IGKV3-11 is also involved in the regulation of cellular processes that are important for the development and maintenance of the immune system. For example, IGKV3-11 has been shown to be involved in the regulation of the production of antibodies, which is important for the immune system.

In conclusion, IGKV3-11 is a protein that is involved in a number of important cellular processes that are important for the development and maintenance of tissues. Its role in the regulation of synapses, cellular signaling pathways, cell division, and the immune system suggests that IGKV3-11 may be a drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of IGKV3-11 in these processes and to determine its potential as a drug or biomarker.

Protein Name: Immunoglobulin Kappa Variable 3-11

Functions: V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170)

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