IGLV10-67: A Potential Drug Target and Biomarker (G28771)

Target Name: IGLV10-67

NCBI ID: G28771

Other Name(s): IGLV1067 | Immunoglobulin lambda variable 10-67 (pseudogene) | immunoglobulin lambda variable 10-67 (pseudogene) | V1-25P

IGLV10-67: A Potential Drug Target and Biomarker

Introduction

The IGF1-like growth factor (IGF) family plays a crucial role in the growth and development of various tissues in the human body. IGF1-67, also known as IGLV10-67, is a member of this family and has been identified as a potential drug target and biomarker. This article will explore IGLV10-67 and its potential applications in the field of drug development.

Potential Drug Target

IGLV10-67 is a protein that is expressed in various tissues throughout the body, including the liver, pancreas, and muscle. It is a 21-kDa protein that consists of an N-terminus, a catalytic domain, and a C-terminus. The N-terminus of IGLV10-67 contains a unique farnesylated cysteine 鈥嬧?媟esidue, which is a hallmark of the IGF1-67 family. This cysteine 鈥嬧?媟esidue is known as a potential drug target for IGLV10-67.

The IGF1-67 family plays a crucial role in the regulation of cell growth, differentiation, and survival. IGF1-67 has been shown to promote the growth and survival of various cell types, including cancer cells. In addition, IGF1-67 has also has been shown to contribute to the development and progression of various diseases, including cancer, obesity, and neurodegenerative disorders.

The potential drug target for IGLV10-67 is its cysteine 鈥嬧?媟esidue, which is known as a site that is vulnerable to drug-induced conformational changes. This residue is also known as a potential drug target for IGLV10-67 because of its role in the regulation of cell signaling pathways.

Potential Biomarkers

IGLV10-67 has also been identified as a potential biomarker for various diseases. For example, IGLV10-67 has been shown to be elevated in the blood and urine of patients with various diseases, including cancer, obesity, and neurodegenerative disorders. This suggests that IGLV10-67 may be a useful biomarker for these diseases.

In addition, IGLV10-67 has also been shown to be regulated by various factors, including cytokines and growth factors. This suggests that IGLV10-67 may be a useful target for drugs that are designed to regulate its activity.

Conclusion

IGLV10-67 is a protein that is expressed in various tissues throughout the body and has been shown to play a crucial role in the regulation of cell growth, differentiation, and survival. The potential drug target for IGLV10-67 is its cysteine 鈥嬧?媟esidue, which is known as a site that is vulnerable to drug-induced conformational changes. IGLV10-67 has also been identified as a potential biomarker for various diseases and may be a useful target for drugs that are designed to regulate its activity. Further research is needed to fully understand the role of IGLV10-67 in the regulation of cell signaling pathways and its potential as a drug target and biomarker.

Protein Name: Immunoglobulin Lambda Variable 10-67 (pseudogene)

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