LCN15: A Potential Drug Target for Cancer (G389812)

Target Name: LCN15

NCBI ID: G389812

LCN15: A Potential Drug Target for Cancer

LCN15 (RP11-216L13.5) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the leucine-rich repeat (LRR) family of proteins, which are characterized by the presence of a leucine residue in their N-terminus.

The RP11 gene is located on chromosome 11 and encodes for the proteinLCN15. This protein is a key regulator of the cell cycle, and is involved in the development and progression of various diseases, including cancer.

One of the unique features of LCN15 is its ability to interact with the protein p53, which is a well-known regulator of the cell cycle and a potential drug target. This interaction between LCN15 and p53 suggests that LCN15 may be a useful biomarker or drug target for the treatment of various diseases, including cancer.

LCN15 has been shown to play a role in the regulation of the cell cycle in various organisms, including bacteria and yeast. For example, studies have shown that LCN15 is involved in the regulation of cell cycle progression in bacteria, and that it promotes the growth and division of cells.

In addition to its role in the cell cycle, LCN15 has also been shown to be involved in the regulation of cell death and survival. This is suggested by the fact that LCN15 has been shown to promote the survival of cancer cells, and that it has been shown to interact with the protein Bcl-2, which is involved in cell death.

The ability of LCN15 to interact with p53 also suggests that it may be a useful drug target for the treatment of cancer. p53 is a well-known regulator of the cell cycle, and has been shown to play a role in the regulation of cell growth and division. By interacting with p53, LCN15 may be able to influence the activity of p53 and disrupt its ability to regulate the cell cycle.

In conclusion, LCN15 is a protein that is expressed in various tissues of the body and is involved in the regulation of the cell cycle. Its ability to interact with the protein p53 suggests that it may be a useful biomarker or drug target for the treatment of various diseases, including cancer. Further research is needed to fully understand the role of LCN15 in the regulation of the cell cycle and its potential as a drug target.

Protein Name: Lipocalin 15

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