Target Name: OR51Q1
NCBI ID: G390061
Other Name(s): O51Q1_HUMAN | olfactory receptor family 51 subfamily Q member 1 | Olfactory receptor family 51 subfamily Q member 1 | Olfactory receptor 51Q1

OR51Q1: Role in BBB and Cellular Processes in Tissues

OR51Q1 (O51Q1_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and pancreas. Its function is not well understood, but it is believed to play a role in the regulation of cellular processes in these tissues.

One of the key functions of OR51Q1 is its role in the regulation of the blood-brain barrier (BBB), which is a specialized barrier that separates the brain from the surrounding bloodstream. The BBB is designed to allow certain molecules and particles into the brain while keeping others out, but it can also selectively allow out certain substances that are not meant to be in the brain.

OR51Q1 is known to be involved in the regulation of the formation and maintenance of the BBB, as well as its remolding process. This means that it is involved in the process of removing or adding materials to the BBB, which is critical for the proper functioning of the barrier.

In addition to its role in the BBB, OR51Q1 is also thought to be involved in the regulation of cellular processes in the liver, as well as the pancreas. It has been shown to be expressed in the liver and pancreas, and to localize to the endoplasmic reticulum (ER) in these tissues.

OR51Q1 is also of interest as a potential drug target, due to its involvement in the regulation of cellular processes that are often disrupted in diseases such as Alzheimer's and Parkinson's. These conditions are characterized by the progressive loss of brain cells and the development of neurodegeneration, and are some of the most common causes of death in older adults.

One way in which OR51Q1 may be targeted as a drug is through its role in the regulation of the blood-brain barrier. Drugs that are able to bypass the BBB and enter the brain, such as those that are used to treat certain types of cancer , may be able to increase the levels of OR51Q1 in the brain and potentially enhance its effects.

Another potential mechanism by which OR51Q1 may be targeted as a drug is its role in the regulation of cellular processes in the liver and pancreas. Conditions such as non-alcoholic fatty liver disease (NAFLD) and diabetes are

Protein Name: Olfactory Receptor Family 51 Subfamily Q Member 1

Functions: Odorant receptor

More Common Targets

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