TRNL1: A Non-Coding RNA Molecule Regulating Gene Expression (G4567)

Target Name: TRNL1

NCBI ID: G4567

TRNL1: A Non-Coding RNA Molecule Regulating Gene Expression

TRNL1 (tRNA Leu UUR) is a small non-coding RNA molecule that plays a crucial role in the regulation of gene expression in various organisms, including humans. TRNL1 is a part of the tRNA machinery, which is responsible for the delivery of amino acids to the ribosome during the process of translation.

TRNL1 is composed of a single exon and is located at position -680 in the 5'-end of the tRNA molecule. It is expressed in most tissues and cells of the body and is involved in the regulation of various cellular processes, including cell growth , differentiation, and protein synthesis.

One of the unique features of TRNL1 is its ability to interact with other molecules, including mRNAs, rRNAs, and proteins. This interaction with other molecules makes TRNL1 a promising drug target and a biomarker for various diseases.

TRNL1 has been shown to play a role in the regulation of gene expression in various organisms, including bacteria, yeast, and plants. For example, studies have shown that TRNL1 can interact with the mRNAs of the bacterial pathogen Mycobacterium tuberculosis and can influence the translation efficiency of the bacteria.

TRNL1 has also been shown to play a role in the regulation of protein synthesis in various organisms. Studies have shown that TRNL1 can interact with the protein translation machinery and can influence the translation efficiency of the bacteria.

In addition to its role in the regulation of gene expression, TRNL1 has also been shown to play a role in the regulation of cellular processes, including cell growth and differentiation. Studies have shown that TRNL1 can interact with the protein kinase Akt and can influence the cell growth and differentiation of the bacteria.

TRNL1 has also been shown to play a role in the regulation of inflammation and immune response. Studies have shown that TRNL1 can interact with the transcription factor NF-kappa-B and can influence the expression of genes involved in inflammation and immune response.

In conclusion, TRNL1 is a small non-coding RNA molecule that plays a crucial role in the regulation of gene expression in various organisms. Its ability to interact with other molecules makes it a promising drug target and a biomarker for various diseases. Further research is needed to fully understand the role of TRNL1 in cellular processes and to develop effective treatments for diseases associated with its dysfunction.

Protein Name: Mitochondrially Encoded TRNA Leucine 1 (UUA/G)

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