MXI1: Key Regulator of Cell-Cell Interactions and Potential Drug Target

Target Name: MXI1

NCBI ID: G4601

MXI1: Key Regulator of Cell-Cell Interactions and Potential Drug Target

MXI1 (MAX interactor 1, dimerization protein) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of cell-cell interactions and has been implicated in a number of diseases, including neurodegenerative disorders, cancer, and cardiomyopathy.

One of the unique features of MXI1 is its ability to dimerize, which means that it can form two copies of itself in the cell. This process is critical for MXI1's function as a regulator of cell-cell interactions and has been implicated in the development and progression of a number of diseases.

MXI1 has been shown to play a role in a number of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. It has also been shown to be involved in the development and progression of cancer, including breast and ovarian cancer.

In addition to its involvement in disease, MXI1 is also a potential drug target. Studies have shown that MXI1 can be targeted with small molecules and that inhibition of its function may be a useful therapy for a number of diseases.

One approach to targeting MXI1 is to use small molecules that specifically interact with its active site. This has been shown to be effective in modulating its function and may be a useful strategy for the development of new treatments for neurodegenerative disorders.

Another approach to targeting MXI1 is to use antibodies that are designed to selectively bind to it. This has been shown to be effective in modulating its function and may be a useful strategy for the development of new treatments for a variety of diseases.

Overall, MXI1 is a protein that has important functions in various tissues and is involved in a number of diseases. Its ability to dimerize and its potential as a drug target make it an attractive target for research into new treatments for a variety of disorders.

Protein Name: MAX Interactor 1, Dimerization Protein

Functions: Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX

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