Target Name: NPR2
NCBI ID: G4882
Other Name(s): guanylyl cyclase B | Atrial natriuretic peptide receptor type B | Guanylate cyclase B | ANP-B | ANPR-B | guanylate cyclase 2B | Atrial natriuretic peptide B-type receptor | NPRBi | Natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) | GUC2B | AMDM | NPR-B | Atrial natriuretic peptide receptor 2 | ANPb | NPRB | atrial natriuretic peptide receptor type B | atrial natriuretic peptide B-type receptor | GC-B | guanylate cyclase B | Natriuretic peptide receptor 2, transcript variant 1 | SNSK | ANPRB_HUMAN | Atrial natriuretic peptide receptor 2 (isoform 1) | GCB | natriuretic peptide receptor 2 | ANPRB | GUCY2B | natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) | NPR2 variant 1 | AMD1 | ECDM

Understanding The Potential Role of NPR2 in Diseases

NPR2, or naphthalene cyclase B, is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Its functions and its role in the biology of these diseases make it an attractive target for researchers to investigate and develop new treatments.

NPR2 is a gene that is expressed in many different tissues and cells in the body. It is a key enzyme in the naphthalene biosynthesis pathway, which is involved in the production of various compounds, including terpenes, which are important for plant aroma and defend against pathogens.

NPR2 has been shown to play a role in the development and progression of various diseases. For example, studies have shown that high levels of naphthalene cyclase B are associated with increased risk of developing cancer. Additionally, higher levels of NPR2 have also been linked to an increased risk of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease.

Furthermore, NPR2 has also been shown to be involved in the development of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In these diseases, the immune system attacks the body's own tissues, leading to inflammation and damage.

Research has also shown that NPR2 is involved in the production of various compounds that are involved in pain signaling and neurotransmission. This suggests that it may be a potential target for pain treatments.

Despite the potential benefits of targeting NPR2, there are also potential drawbacks to consider. One concern is that it is a gene that has not yet been fully studied, which could make it difficult to fully understand its role in the body and develop effective treatments. Additionally, it is also a gene that is expressed in many different tissues, which could make it difficult to target specific changes in the body.

Despite these challenges, the potential benefits of targeting NPR2 make it an attractive target for researchers to investigate. With further research, it may be found that NPR2 plays a critical role in the development and progression of various diseases, and targeting it may lead to new treatments for these conditions.

Protein Name: Natriuretic Peptide Receptor 2

Functions: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth

More Common Targets

NPR3 | NPRL2 | NPRL3 | NPS | NPSR1 | NPSR1-AS1 | NPTN | NPTN-IT1 | NPTX1 | NPTX2 | NPTXR | NPVF | NPW | NPY | NPY1R | NPY2R | NPY4R | NPY4R2 | NPY5R | NPY6R | NQO1 | NQO2 | NR0B1 | NR0B2 | NR1D1 | NR1D2 | NR1H2 | NR1H3 | NR1H4 | NR1I2 | NR1I3 | NR2C1 | NR2C2 | NR2C2AP | NR2E1 | NR2E3 | NR2F1 | NR2F1-AS1 | NR2F2 | NR2F2-AS1 | NR2F6 | NR3C1 | NR3C2 | NR4A1 | NR4A2 | NR4A3 | NR5A1 | NR5A2 | NR6A1 | NRAD1 | NRADDP | NRAP | NRARP | NRAS | NRAV | NRBF2 | NRBF2P4 | NRBP1 | NRBP2 | NRCAM | NRDC | NRDE2 | NREP | NRF1 | NRG1 | NRG2 | NRG3 | NRG4 | NRGN | NRIP1 | NRIP2 | NRIP3 | NRIP3-DT | NRIR | NRK | NRL | NRM | NRN1 | NRN1L | NRON | NRP1 | NRP2 | NRROS | NRSN1 | NRSN2 | NRSN2-AS1 | NRTN | NRXN1 | NRXN2 | NRXN2-AS1 | NRXN3 | NSA2 | NSA2P2 | NSD1 | NSD2 | NSD3 | NSDHL | NSF | NSFL1C | NSFP1