Target Name: MIR376A1
NCBI ID: G494325
Other Name(s): hsa-mir-376a-1 | hsa-miR-376a-5p | microRNA 376a-1 | MIR376A-1 | MIRN376A-1 | MIRN376A | MicroRNA 376a-1 | hsa-miR-376a-3p | MIRN376A1 | mir-376a-1

MIR376A1: A Potential Drug Target and Biomarker

MIR376A1, a protein encoded by the human gene HTTN1, is a potential drug target and biomarker associated with various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Its function and interactions with other proteins have been extensively studied, providing insights into its potential as a therapeutic target or diagnostic marker.

MIR376A1 is a non-coding RNA molecule that has been shown to play a critical role in various cellular processes, including cell growth, differentiation, and survival. It is a part of the microRNA (miRNA) family, a set of small non-coding RNAs that are involved in post-transcriptional gene regulation. miRNAs have been shown to regulate gene expression by binding to specific target genes, often leading to the targeted translation of mRNAs for degradation or degradation-inducing translation.

MIR376A1 has been shown to regulate the expression of various genes, including those involved in cell growth, differentiation, and apoptosis. It has been shown to promote the translation of survival-related genes, such as Bcl-2, which is known to play a critical role in preventing apoptosis and promoting cell survival. MIR376A1 has also been shown to repress the translation of pro-apoptotic genes, including p53, which is involved in the regulation of cell cycle and apoptosis.

In addition to its role in cell survival, MIR376A1 has also been shown to be involved in the regulation of cell proliferation. It has been shown to promote the growth of various types of cancer cells and to contribute to the development of various types of cancer. This is thought to be achieved by regulating the translation of genes involved in cell growth and proliferation, such as the TGF-β pathway.

MIR376A1 has also been shown to be involved in the regulation of cellular processes related to neurodegenerative disorders. It has been shown to contribute to the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. This is thought to be achieved by regulating the translation of genes involved in neurodegeneration, such as the 尾-amyloid (尾-amyloid) pathway.

In addition to its role in neurodegenerative diseases, MIR376A1 has also been shown to be involved in the regulation of cardiovascular diseases. It has been shown to contribute to the development and progression of cardiovascular diseases, including heart failure and hypertension. This is thought to be Achieved by regulating the translation of genes involved in cardiovascular function, such as the angiotensin-converting enzyme (ACE) pathway.

MIR376A1 is a potential drug target due to its involvement in various cellular processes that are related to the development and progression of various diseases. Its role in cell survival and proliferation, as well as its involvement in the regulation of neurodegenerative and cardiovascular diseases, make it an attractive target for therapeutic intervention. Further research is needed to fully understand the role of MIR376A1 in these diseases and to develop effective treatments based on this understanding.

Protein Name: MicroRNA 376a-1

More Common Targets

MIR376A2 | MIR376B | MIR376C | MIR377 | MIR378A | MIR378B | MIR378C | MIR378D1 | MIR378D2 | MIR378E | MIR378F | MIR378G | MIR378H | MIR378I | MIR379 | MIR380 | MIR381 | MIR382 | MIR383 | MIR384 | MIR3907 | MIR3908 | MIR3909 | MIR3910-1 | MIR3910-2 | MIR3911 | MIR3912 | MIR3913-1 | MIR3913-2 | MIR3914-1 | MIR3914-2 | MIR3915 | MIR3916 | MIR3917 | MIR3918 | MIR3919 | MIR3920 | MIR3921 | MIR3922 | MIR3923 | MIR3924 | MIR3925 | MIR3926-1 | MIR3926-2 | MIR3927 | MIR3928 | MIR3929 | MIR3934 | MIR3935 | MIR3936 | MIR3936HG | MIR3937 | MIR3938 | MIR3939 | MIR3940 | MIR3941 | MIR3942 | MIR3943 | MIR3944 | MIR3945 | MIR3945HG | MIR3960 | MIR3972 | MIR3973 | MIR3974 | MIR3976 | MIR3976HG | MIR3977 | MIR3978 | MIR409 | MIR410 | MIR411 | MIR412 | MIR421 | MIR422A | MIR423 | MIR424 | MIR425 | MIR4251 | MIR4252 | MIR4253 | MIR4254 | MIR4255 | MIR4256 | MIR4257 | MIR4258 | MIR4259 | MIR4260 | MIR4261 | MIR4262 | MIR4263 | MIR4264 | MIR4265 | MIR4266 | MIR4267 | MIR4268 | MIR4269 | MIR4270 | MIR4271 | MIR4272