hTLP19: A Protein Implicated in Cancer and Other Diseases (G51060)

Target Name: TXNDC12

NCBI ID: G51060

hTLP19: A Protein Implicated in Cancer and Other Diseases

hTLP19, also known as TXNDC12, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the T-cell nuclear factor of the DNA-binding complex (TNFC), which plays a role in regulating gene expression and DNA replication. hTLP19 has also been shown to be involved in the regulation of cellular processes that are important for the development and progression of various diseases, including cancer.

One of the key functions of hTLP19 is its role in the regulation of apoptosis, which is the process by which cells undergo programmed cell death. Apoptosis is a natural and important part of the immune system, as it helps to eliminate damaged or dysfunctional cells. However, when apoptosis is not properly regulated, it can lead to the development of cancer.

hTLP19 has been shown to play a role in the regulation of apoptosis in various tissues and organs, including the brain. Studies have shown that hTLP19 can induce apoptosis in brain cells under certain conditions, such as exposure to chemotherapy drugs or radiation. This suggests that hTLP19 may be a potential drug target for the treatment of certain types of cancer.

Another function of hTLP19 is its role in the regulation of cell proliferation. hTLP19 has been shown to play a negative role in the regulation of cell proliferation, which means that when hTLP19 is present in a cell, it can inhibit the ability of that cell to divide and grow. This is important because uncontrolled cell proliferation is a hallmark of many diseases, including cancer.

hTLP19 has also been shown to be involved in the regulation of cellular interactions with the blood vessels that supply different tissues and organs. This is important because the blood vessels are a critical source of oxygen and nutrients for many cells, and they are also a major site of damage in many diseases. hTLP19 has been shown to play a role in the regulation of the formation and function of blood vessels, which may be important for the development and progression of many diseases.

In addition to its role in the regulation of apoptosis, hTLP19 has also been shown to be involved in the regulation of cell signaling pathways that are important for the development and progression of many diseases. For example, hTLP19 has been shown to play a role in the regulation of the signaling pathway known as the T-cell signaling pathway. This pathway is important for the development and regulation of T-cells, which are a critical part of the immune system.

Overall, hTLP19 is a protein that has been shown to play a role in a variety of cellular processes that are important for the development and progression of many diseases. As a result, it is a potential drug target for the treatment of a wide range of conditions, including cancer. Further research is needed to fully understand the role of hTLP19 in the regulation of cellular processes and to develop effective treatments for the various diseases in which it is involved.

Protein Name: Thioredoxin Domain Containing 12

Functions: Protein-disulfide reductase of the endoplasmic reticulum that promotes disulfide bond formation in client proteins through its thiol-disulfide oxidase activity

More Common Targets